Vitamin K Bone Mineral Density Randomized Trial: What the Evidence Says

Quick Answer

Vitamin K Bone Mineral Density Randomized Trial has 2 source documents in the current Migaku evidence database. The strongest available sources in this first pass are systematic review, randomized trial, so conclusions should be framed as evidence-aware guidance rather than medical advice.

Key Takeaways

• This page is generated only from sources stored in the Migaku evidence knowledge base.
• Current evidence mix: 1 systematic review, 1 randomized trial.
• Claims should be interpreted with the source type, study design, population, and publication date in mind.
• This article is educational and does not replace care from a qualified clinician.

Evidence Map

What The Sources Report

• Objectives: The purpose of the present systematic review was to summarize the evidence from the randomized controlled studies on the effect of prunes on bone health in humans and to pool the results in a meta-analysis. [Treister-Goltzman Y (2026); evidence level 1]
• The effect of prune intervention in postmenopausal women was borderline significant at the lumbar spine, with BMD slightly higher in the intervention group (SMD [95% CI] = 1.30 [-0.03, 2.63]; I 2 = 98%; p Conclusions: Our meta-analysis provides preliminary evidence of modest skeletal benefits associated with consumption of 50-100 g of prunes, particularly at the lumbar spine, a trabecular-rich site. [Treister-Goltzman Y (2026); evidence level 1]
• Effects of Eggshell Calcium- and Vitamin D-Fortified HMR Combined with Aerobic Exercise on Bone Mineral Density in Postmenopausal Women: A Pilot Randomized Controlled Trial [Jung S (2026); evidence level 2]

How To Read This Evidence

Evidence level 1 generally reflects systematic reviews or meta-analyses. Level 2 includes randomized trials, guidelines, or public-health guidance. Level 3 usually reflects observational or narrative-review evidence. Level 4 is weaker or early-stage evidence. The level is a sorting aid, not a final quality grade.

Practical Interpretation

There is at least one systematic-review style source in the current set, so it deserves more weight than single-study evidence. There is trial evidence in the current set, but population and intervention details still matter. For vitamin K bone mineral density randomized trial, the next editorial step is to add more targeted sources and separate strong findings from early or indirect evidence.

Limits Of This First Pass

This is a small-batch MVP article. It uses the first ingested sources for this topic and should be expanded with more targeted searches, license review, and human editorial checks before being treated as a definitive review.

References

• Treister-Goltzman Y (2026). Effects of Prunes on Bone Density in Humans: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.. DOI: 10.3390/nu18091338. PMCID: PMC13164729. PMID: 42123941. https://pmc.ncbi.nlm.nih.gov/articles/PMC13164729/
• Jung S (2026). Effects of Eggshell Calcium- and Vitamin D-Fortified HMR Combined with Aerobic Exercise on Bone Mineral Density in Postmenopausal Women: A Pilot Randomized Controlled Trial. PMCID: PMC12942995. https://pmc.ncbi.nlm.nih.gov/articles/PMC12942995/

Safety Note

Health information can change, and individual risk depends on medical history, medications, pregnancy status, age, and diagnosis. Talk with a qualified clinician before changing treatment, supplement, or medication routines.