topicVitamin K Bone Mineral Density Meta-Analysis
claimThe worldwide health organization considers osteoporosis and its associated fragile bone breaks to be two of the most serious public health issues because they affect more than 200 million people who have osteoporosis according to its estimates and women and men above 50 years of age face a lifetime fracture risk that exceeds 50 percent and 20 percent, respectively ().
evidence level1
citationLv Chen (2026)
sourceEffects of macro- and micronutrient intake on bone mineral density, osteoporotic fracture risk, inflammation, and functional rehabilitation outcomes in orthopedic patients: a systematic review and meta-analysis
topicVitamin K Bone Mineral Density Meta-Analysis
claimThe economic costs which result from fracture-related health problems create a significant financial burden while they result in extended periods of disability and independence loss and they increase the risk of death which demonstrates that society needs to develop better methods for both preventing and treating these conditions ().
evidence level1
citationLv Chen (2026)
sourceEffects of macro- and micronutrient intake on bone mineral density, osteoporotic fracture risk, inflammation, and functional rehabilitation outcomes in orthopedic patients: a systematic review and meta-analysis
topicVitamin K Bone Mineral Density Meta-Analysis
claimIncreased levels of the inflammatory cytokines TNF-and IL-6 and CRP lead to faster bone loss and slower bone healing and more difficulties after surgery.
evidence level1
citationLv Chen (2026)
sourceEffects of macro- and micronutrient intake on bone mineral density, osteoporotic fracture risk, inflammation, and functional rehabilitation outcomes in orthopedic patients: a systematic review and meta-analysis
topicVitamin K Bone Mineral Density Meta-Analysis
claim1 2 3–5 Bone health serves as the essential factor that determines how musculoskeletal systems operate and how much people enjoy their lives and how often they experience health problems in particular for elderly individuals and people with orthopedic conditions.
evidence level1
citationLv Chen (2026)
sourceEffects of macro- and micronutrient intake on bone mineral density, osteoporotic fracture risk, inflammation, and functional rehabilitation outcomes in orthopedic patients: a systematic review and meta-analysis
topicVitamin K Bone Mineral Density Meta-Analysis
claim1 2 1 2 Osteoporosis, the primary risk factor for fragility fractures, is highly prevalent and projected to increase as populations age globally [,].
evidence level1
citationTreister-Goltzman Yulia (2026)
sourceEffects of Prunes on Bone Density in Humans: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
topicVitamin K Bone Mineral Density Meta-Analysis
claimFragility fractures, particularly of the hip, spine, and wrist, are associated with substantial morbidity, loss of independence, increased mortality, and considerable healthcare costs, making osteoporosis a significant public health concern [,].
evidence level1
citationTreister-Goltzman Yulia (2026)
sourceEffects of Prunes on Bone Density in Humans: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
topicVitamin K Bone Mineral Density Meta-Analysis
claimEvidence from multiple in vitro biochemical and cell culture studies [,,], as well as preclinical investigations using ovariectomized and estrogen-deficient rodent models [,,,,,], consistently supports a favorable effect of prunes or prune-derived components on bone metabolism.
evidence level1
citationTreister-Goltzman Yulia (2026)
sourceEffects of Prunes on Bone Density in Humans: A Systematic Review and Meta-Analysis of Randomized Controlled Trials