Is Vitamin K Bone Mineral Density Randomized Trial safe?

Updated June 2026

Quick Answer

Vitamin K Bone Mineral Density Randomized Trial has evidence relevant to safety, limits, and clinician-discussion contexts, but conclusions should stay close to the cited sources. One representative finding is: Objectives: The purpose of the present systematic review was to summarize the evidence from the randomized controlled studies on the effect of prunes on bone health in humans and to pool the results in a meta-analysis.

Key Takeaways

  • 01Objectives: The purpose of the present systematic review was to summarize the evidence from the randomized controlled studies on the effect of prunes on bone health in humans and to pool the results in a meta-analysis. [Treister-Goltzman Y (2026)]
  • 02The effect of prune intervention in postmenopausal women was borderline significant at the lumbar spine, with BMD slightly higher in the intervention group (SMD [95% CI] = 1.30 [-0.03, 2.63]; I 2 = 98%; p Conclusions: Our meta-analysis provides preliminary evidence of modest skeletal benefits associated with consumption of 50-100 g of prunes, particularly at the lumbar spine, a trabecular-rich site. [Treister-Goltzman Y (2026)]
  • 03Background: Recent studies suggest that prunes are one of the most effective fruits for preventing and reversing bone loss. [Treister-Goltzman Y (2026)]
  • 04Effects of Eggshell Calcium- and Vitamin D-Fortified HMR Combined with Aerobic Exercise on Bone Mineral Density in Postmenopausal Women: A Pilot Randomized Controlled Trial [Jung S (2026)]
The current Migaku evidence database contains 2 reusable source documents for Vitamin K Bone Mineral Density Randomized Trial. This answer focuses on safety, limits, and clinician-discussion contexts. - Objectives: The purpose of the present systematic review was to summarize the evidence from the randomized controlled studies on the effect of prunes on bone health in humans and to pool the results in a meta-analysis. [Treister-Goltzman Y (2026); evidence level 1] - The effect of prune intervention in postmenopausal women was borderline significant at the lumbar spine, with BMD slightly higher in the intervention group (SMD [95% CI] = 1.30 [-0.03, 2.63]; I 2 = 98%; p Conclusions: Our meta-analysis provides preliminary evidence of modest skeletal benefits associated with consumption of 50-100 g of prunes, particularly at the lumbar spine, a trabecular-rich site. [Treister-Goltzman Y (2026); evidence level 1] - Background: Recent studies suggest that prunes are one of the most effective fruits for preventing and reversing bone loss. [Treister-Goltzman Y (2026); evidence level 1] - Effects of Eggshell Calcium- and Vitamin D-Fortified HMR Combined with Aerobic Exercise on Bone Mineral Density in Postmenopausal Women: A Pilot Randomized Controlled Trial [Jung S (2026); evidence level 2] Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording. This page is educational. People with medical conditions, pregnancy, medication use, or unusual symptoms should ask a qualified clinician before changing supplements, medication, or treatment routines.

Sources

  1. Effects of Prunes on Bone Density in Humans: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
  2. Effects of Eggshell Calcium- and Vitamin D-Fortified HMR Combined with Aerobic Exercise on Bone Mineral Density in Postmenopausal Women: A Pilot Randomized Controlled Trial