Structured evidence table for Vitamin K2 Fracture Risk Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Vitamin K2 Fracture Risk Meta-Analysis | The study used the Jadad scale and Cochrane Risk of Bias and GRADE criteria to evaluate study quality while the researchers used funnel plots and Egger's test to assess publication bias. | 1 | Lv C (2026) | Effects of macro- and micronutrient intake on bone mineral density, osteoporotic fracture risk, inflammation, and functional rehabilitation outcomes in orthopedic patients: a systematic review and meta-analysis. |
| Vitamin K2 Fracture Risk Meta-Analysis | Results Interventions significantly improved BMD (SMD = 0.47; 95% CI: 0.31-0.62; p 2 = 79%), bone turnover markers (SMD = -0.69; 95% CI: -1.17 to -0.20; p = 0.004; I 2 = 99%), inflammation/oxidative stress markers (SMD = -1.34; 95% CI: -1.45 to -1.23; p 2 = 0%), and postoperative recovery/metabolic outcomes (SMD = -2.04; 95% CI: -2.31 to -1.77; p 2 = 86%). | 1 | Lv C (2026) | Effects of macro- and micronutrient intake on bone mineral density, osteoporotic fracture risk, inflammation, and functional rehabilitation outcomes in orthopedic patients: a systematic review and meta-analysis. |
| Vitamin K2 Fracture Risk Meta-Analysis | Conclusion The study results demonstrate that nutritional and therapeutic treatments lead to better bone density results together with improved biochemical markers and reduced inflammation and faster recovery after surgery. | 1 | Lv C (2026) | Effects of macro- and micronutrient intake on bone mineral density, osteoporotic fracture risk, inflammation, and functional rehabilitation outcomes in orthopedic patients: a systematic review and meta-analysis. |
| Vitamin K2 Fracture Risk Meta-Analysis | Background Nutritional and therapeutic methods are used to enhance bone health and assist in fracture healing while improving functional ability and reducing inflammation and bettering surgical results. | 1 | Lv C (2026) | Effects of macro- and micronutrient intake on bone mineral density, osteoporotic fracture risk, inflammation, and functional rehabilitation outcomes in orthopedic patients: a systematic review and meta-analysis. |
| Vitamin K2 Fracture Risk Meta-Analysis | In the Global Burden of Disease 2019 analysis, low bone mineral density was associated with about 438,000 deaths and 166 million disability-adjusted life years, with large increases since 1990 (). | 1 | Zhang Zechen (2025) | The effect of vitamin K2 supplementation on bone turnover biochemical markers in postmenopausal osteoporosis patients: a systematic review and meta-analysis |
| Vitamin K2 Fracture Risk Meta-Analysis | In a cross-sectional study of 900 Chinese adults, higher ucOC was associated with lower BMD at the spine, femoral neck, and hip, and with higher P1NP and β-CTX, indicating increased turnover (). | 1 | Zhang Zechen (2025) | The effect of vitamin K2 supplementation on bone turnover biochemical markers in postmenopausal osteoporosis patients: a systematic review and meta-analysis |
| Vitamin K2 Fracture Risk Meta-Analysis | K2 deficiency has been linked to the “calcium paradox,” with insufficient skeletal deposition and increased vascular calcification (). | 1 | Zhang Zechen (2025) | The effect of vitamin K2 supplementation on bone turnover biochemical markers in postmenopausal osteoporosis patients: a systematic review and meta-analysis |
| Vitamin K2 Fracture Risk Meta-Analysis | It is characterized by low bone mass and deterioration of bone microarchitecture. | 1 | Zhang Zechen (2025) | The effect of vitamin K2 supplementation on bone turnover biochemical markers in postmenopausal osteoporosis patients: a systematic review and meta-analysis |
Source documents