topicVitamin K2 Blood Pressure Randomized Trial
claimBackground/Objectives : Obesity in young adults is a major public health concern and a key contributor to cardiometabolic risk.
evidence level2
citationOlivares-Ochoa XC (2026)
sourceVitamin K2 Supplementation Reduces Cardiometabolic Risk Factors in Young Adults with Overweight and Obesity-A Randomized Placebo-Controlled Trial.
topicVitamin K2 Blood Pressure Randomized Trial
claimVitamin K2 (VK2) has been proposed as a potential adjuvant therapy; however, evidence from randomized controlled trials remains limited.
evidence level2
citationOlivares-Ochoa XC (2026)
sourceVitamin K2 Supplementation Reduces Cardiometabolic Risk Factors in Young Adults with Overweight and Obesity-A Randomized Placebo-Controlled Trial.
topicVitamin K2 Blood Pressure Randomized Trial
claimThis study evaluated the effect of VK2 supplementation on cardiometabolic risk factors in young adults with overweight or obesity.
evidence level2
citationOlivares-Ochoa XC (2026)
sourceVitamin K2 Supplementation Reduces Cardiometabolic Risk Factors in Young Adults with Overweight and Obesity-A Randomized Placebo-Controlled Trial.
topicVitamin K2 Blood Pressure Randomized Trial
claimVitamin D deficiency has been consistently associated with adverse outcomes, including increased susceptibility to cancers, diabetes, hypertension, and cardiovascular disease [,].
evidence level3
citationD’Elia Saverio (2025)
sourceModulation of Cardiometabolic Risk by Vitamin D and K2: Simple Supplementation or Real Drug? Uncovering the Pharmacological Properties
topicVitamin K2 Blood Pressure Randomized Trial
claimEpidemiological studies further indicate that populations in regions with higher sun exposure exhibit lower prevalence of deficiency and reduced mortality from chronic disease [,].
evidence level3
citationD’Elia Saverio (2025)
sourceModulation of Cardiometabolic Risk by Vitamin D and K2: Simple Supplementation or Real Drug? Uncovering the Pharmacological Properties
topicVitamin K2 Blood Pressure Randomized Trial
claimThese findings are reinforced by recent large-scale analyses: for example, a 2023 study in Clinical Nutrition involving nearly 410,000 UK Biobank participants reported that individuals with severe deficiency (<30 nmol/L) had a 10% increased risk of atherosclerotic cardiovascular disease and up to 35% higher risk of cardiovascular mortality [].
evidence level3
citationD’Elia Saverio (2025)
sourceModulation of Cardiometabolic Risk by Vitamin D and K2: Simple Supplementation or Real Drug? Uncovering the Pharmacological Properties
topicVitamin K2 Blood Pressure Randomized Trial
claim1 2 3 4 5 6 7 6 Vitamin D, a pleiotropic secosteroid, exerts physiological effects far beyond its classical roles in calcium homeostasis and skeletal health [].
evidence level3
citationD’Elia Saverio (2025)
sourceModulation of Cardiometabolic Risk by Vitamin D and K2: Simple Supplementation or Real Drug? Uncovering the Pharmacological Properties