Structured evidence table for Vitamin K Fracture Meta-Analysis, generated from 4 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Vitamin K Fracture Meta-Analysis | Secondary outcomes included the risk of hip fracture, non-vertebral fracture, vertebral fracture, and falling, as well as the total number of falls. | 1 | Massé O (2026) | Calcium, vitamin D, or combined supplementation to prevent fractures and falls: systematic review and meta-analysis. |
| Vitamin K Fracture Meta-Analysis | Pairs of reviewers independently screened trials, extracted data, and assessed risk of bias using the second version of Cochrane's risk of bias tool. | 1 | Massé O (2026) | Calcium, vitamin D, or combined supplementation to prevent fractures and falls: systematic review and meta-analysis. |
| Vitamin K Fracture Meta-Analysis | Participants in most of the trials were community dwelling (87%) and not at high risk of fractures or falls (73%). | 1 | Massé O (2026) | Calcium, vitamin D, or combined supplementation to prevent fractures and falls: systematic review and meta-analysis. |
| Vitamin K Fracture Meta-Analysis | Objective To assess the effect of calcium, vitamin D, or combined supplementation on fractures and falls in adults. | 1 | Massé O (2026) | Calcium, vitamin D, or combined supplementation to prevent fractures and falls: systematic review and meta-analysis. |
| Vitamin K Fracture Meta-Analysis | The worldwide health organization considers osteoporosis and its associated fragile bone breaks to be two of the most serious public health issues because they affect more than 200 million people who have osteoporosis according to its estimates and women and men above 50 years of age face a lifetime fracture risk that exceeds 50 percent and 20 percent, respectively (). | 1 | Lv Chen (2026) | Effects of macro- and micronutrient intake on bone mineral density, osteoporotic fracture risk, inflammation, and functional rehabilitation outcomes in orthopedic patients: a systematic review and meta-analysis |
| Vitamin K Fracture Meta-Analysis | The economic costs which result from fracture-related health problems create a significant financial burden while they result in extended periods of disability and independence loss and they increase the risk of death which demonstrates that society needs to develop better methods for both preventing and treating these conditions (). | 1 | Lv Chen (2026) | Effects of macro- and micronutrient intake on bone mineral density, osteoporotic fracture risk, inflammation, and functional rehabilitation outcomes in orthopedic patients: a systematic review and meta-analysis |
| Vitamin K Fracture Meta-Analysis | Increased levels of the inflammatory cytokines TNF-and IL-6 and CRP lead to faster bone loss and slower bone healing and more difficulties after surgery. | 1 | Lv Chen (2026) | Effects of macro- and micronutrient intake on bone mineral density, osteoporotic fracture risk, inflammation, and functional rehabilitation outcomes in orthopedic patients: a systematic review and meta-analysis |
| Vitamin K Fracture Meta-Analysis | 1 2 3–5 Bone health serves as the essential factor that determines how musculoskeletal systems operate and how much people enjoy their lives and how often they experience health problems in particular for elderly individuals and people with orthopedic conditions. | 1 | Lv Chen (2026) | Effects of macro- and micronutrient intake on bone mineral density, osteoporotic fracture risk, inflammation, and functional rehabilitation outcomes in orthopedic patients: a systematic review and meta-analysis |
| Vitamin K Fracture Meta-Analysis | 1 2 1 2 3 4 Osteoporosis is a serious bone disease characterized by reduced bone mass and deterioration of the bone microarchitecture, leading to an increased risk of fractures. | 3 | Gasser Rudolf Wolfgang (2026) | Drug-Induced Osteoporosis |
| Vitamin K Fracture Meta-Analysis | While glucocorticoids (GCs) are assumed to have a bimodal mode of action (increased resorption followed by reduced osteoanabolic activity), other drugs mainly induce increased bone resorption. | 3 | Gasser Rudolf Wolfgang (2026) | Drug-Induced Osteoporosis |
| Vitamin K Fracture Meta-Analysis | Finally, certain medications can lead to an increased tendency to fall and thus to a higher risk of fractures. | 3 | Gasser Rudolf Wolfgang (2026) | Drug-Induced Osteoporosis |
| Vitamin K Fracture Meta-Analysis | A complex interplay of osteoblasts, osteoclasts, and osteocytes leads to a regulated process of bone formation and resorption, whereby in osteoporosis, bone formation cannot sufficiently replace bone resorption. | 3 | Gasser Rudolf Wolfgang (2026) | Drug-Induced Osteoporosis |
Source documents