Structured evidence table for Vitamin E Cognitive Performance Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Vitamin E Cognitive Performance Meta-Analysis | In the late-onset groups, the apolipoprotein E (APOE) gene, the strongest and most consistently replicated genetic risk factor, is associated with AD. | 3 | Lawal Rasheedat (2026) | Interactions Between Blood Nutritional Biomarkers and Apolipoprotein E ε4 in the Progression of Mild Cognitive Impairment in Alzheimer’s Disease |
| Vitamin E Cognitive Performance Meta-Analysis | The ε4 allele increases the likelihood of developing AD and is associated with greater neuroinflammation and impaired lipid transport []. | 3 | Lawal Rasheedat (2026) | Interactions Between Blood Nutritional Biomarkers and Apolipoprotein E ε4 in the Progression of Mild Cognitive Impairment in Alzheimer’s Disease |
| Vitamin E Cognitive Performance Meta-Analysis | 2 16 17 18 14 19 18 Although individuals with MCI face an elevated risk of progression to Alzheimer’s disease [,,], if not controlled properly [], the trajectories are highly variable. | 3 | Lawal Rasheedat (2026) | Interactions Between Blood Nutritional Biomarkers and Apolipoprotein E ε4 in the Progression of Mild Cognitive Impairment in Alzheimer’s Disease |
| Vitamin E Cognitive Performance Meta-Analysis | 1 2 3 4 Alzheimer’s disease (AD) is the most common cause of dementia [], which accounts for 55.2 million dementia cases estimated globally and is projected to exceed 75.6 million cases by 2030 []. | 3 | Lawal Rasheedat (2026) | Interactions Between Blood Nutritional Biomarkers and Apolipoprotein E ε4 in the Progression of Mild Cognitive Impairment in Alzheimer’s Disease |
| Vitamin E Cognitive Performance Meta-Analysis | This review summarizes current evidence on nutritional compounds that target aging-related pathways, focusing on interventions that influence mitochondrial health, cognitive performance, immune function, metabolic regulation, and maintenance of muscle mass in older adults. | 4 | Kurtz JA (2026) | Targeted Supplementation and Nutritional Strategies for Healthy Aging: A Review of Physiological and Molecular Benefits. |
| Vitamin E Cognitive Performance Meta-Analysis | Recent findings Evidence indicates that several targeted nutrients, including protein, probiotics, antioxidants, and emerging mitochondrial-support compounds, may contribute to healthy aging. | 4 | Kurtz JA (2026) | Targeted Supplementation and Nutritional Strategies for Healthy Aging: A Review of Physiological and Molecular Benefits. |
| Vitamin E Cognitive Performance Meta-Analysis | A personalized, evidence-informed supplementation strategy integrated with exercise and balanced nutrition may help optimize physiological function in aging adults. | 4 | Kurtz JA (2026) | Targeted Supplementation and Nutritional Strategies for Healthy Aging: A Review of Physiological and Molecular Benefits. |
| Vitamin E Cognitive Performance Meta-Analysis | Purpose of review Aging is marked by progressive physiological decline driven by chronic inflammation, mitochondrial dysfunction, and impaired metabolic and musculoskeletal resilience. | 4 | Kurtz JA (2026) | Targeted Supplementation and Nutritional Strategies for Healthy Aging: A Review of Physiological and Molecular Benefits. |
Source documents