evidence table
Vitamin D Strength Meta-Analysis Evidence Table
Structured evidence table for Vitamin D Strength Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Vitamin D Strength Meta-Analysis | 1 2 3 4 Sarcopenia is a condition characterized by the progressive and generalized loss of muscle mass and function that primarily affects the older adult population, compromising their autonomy and quality of life, as it associated with a significantly increased risk of falls, hospitalizations, and mortality (). | 3 | Calderón Paula (2026) | The role of protein quality and amino acid composition in preventing sarcopenia and functional decline in older adults |
| Vitamin D Strength Meta-Analysis | One of the cornerstones of the prevention and treatment of sarcopenia is a protein-rich diet; however, current evidence suggests that standard protein intake recommendations may be insufficient to overcome the “anabolic resistance” characteristic of advanced age (,). | 3 | Calderón Paula (2026) | The role of protein quality and amino acid composition in preventing sarcopenia and functional decline in older adults |
| Vitamin D Strength Meta-Analysis | The main molecular mechanisms, mediated by NF- κB, mTOR, and TGF- β, involved in cellular senescence are associated with the activation of transcriptional programs that regulate gene expression, signaling pathways, and metabolism regulators, developing a senescence-associated secretory phenotype (SASP) (,). | 3 | Calderón Paula (2026) | The role of protein quality and amino acid composition in preventing sarcopenia and functional decline in older adults |
| Vitamin D Strength Meta-Analysis | This is due to age-related mechanisms of cellular senescence, oxidative stress, and low-grade chronic inflammation, all factors that exacerbate muscle catabolism and limit the regenerative capacity of the muscle tissue during aging (). | 3 | Calderón Paula (2026) | The role of protein quality and amino acid composition in preventing sarcopenia and functional decline in older adults |
| Vitamin D Strength Meta-Analysis | This emerging area highlights how genetic differences shape vitamin D absorption, metabolism, transport, and cellular action, ultimately influencing disease risk and health outcomes. | 3 | Qahtan Fatima (2026) | Genetic and epigenetic determinants of vitamin D metabolism: nutrigenomic insights for precision nutrition |
| Vitamin D Strength Meta-Analysis | In this context, this review synthesizes selected evidence on the genetic, epigenetic, and molecular determinants of vitamin D metabolism, with the aim of critically evaluating the strength, consistency, and limitations of current nutrigenomic findings and clarifying their implications and constraints for personalized nutrition and disease prevention. | 3 | Qahtan Fatima (2026) | Genetic and epigenetic determinants of vitamin D metabolism: nutrigenomic insights for precision nutrition |
| Vitamin D Strength Meta-Analysis | This limit understanding of how multiple genetic, epigenetic, and nutrigenomic factors work together to influence vitamin D status and disease risk. | 3 | Qahtan Fatima (2026) | Genetic and epigenetic determinants of vitamin D metabolism: nutrigenomic insights for precision nutrition |
| Vitamin D Strength Meta-Analysis | 1 Vitamin D is one of the most extensively studied micronutrients in modern nutritional science, particularly because of its wide-ranging effects on immune regulation, metabolic function, bone health, and gene expression. | 3 | Qahtan Fatima (2026) | Genetic and epigenetic determinants of vitamin D metabolism: nutrigenomic insights for precision nutrition |
Source documents