Structured evidence table for Vitamin D Sleep Quality Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Vitamin D Sleep Quality Randomized Trial | However, the evidence base for TCM pharmacologic interventions in hemodialysis-related RLS remains unclear. | 1 | Zhang J (2026) | Efficacy and safety of pharmacological treatments for restless legs syndrome in hemodialysis patients: a systematic review and meta-analysis. |
| Vitamin D Sleep Quality Randomized Trial | Pharmacologic therapy significantly improved IRLS scores (MD -7.84), sleep quality (SMD -0.82), and quality of life (SMD 0.48). | 1 | Zhang J (2026) | Efficacy and safety of pharmacological treatments for restless legs syndrome in hemodialysis patients: a systematic review and meta-analysis. |
| Vitamin D Sleep Quality Randomized Trial | A heatmap further revealed that dopaminergic agents were associated with the highest frequency of adverse events, particularly nausea, hypotension, and augmentation. | 1 | Zhang J (2026) | Efficacy and safety of pharmacological treatments for restless legs syndrome in hemodialysis patients: a systematic review and meta-analysis. |
| Vitamin D Sleep Quality Randomized Trial | Background Restless Legs Syndrome (RLS) is highly prevalent among adults receiving maintenance hemodialysis and significantly impairs sleep, psychological well-being, and quality of life. | 1 | Zhang J (2026) | Efficacy and safety of pharmacological treatments for restless legs syndrome in hemodialysis patients: a systematic review and meta-analysis. |
| Vitamin D Sleep Quality Randomized Trial | Hypertension represents the predominant risk factor for cardiovascular disease morbidity and mortality; with significant healthcare utilization and expenditure. | 2 | Sinclair J (2026) | Effects of peppermint (Mentha x piperita L.) oil on cardiometabolic outcomes in patients with pre- and stage 1 hypertension: A placebo randomized controlled trial. |
| Vitamin D Sleep Quality Randomized Trial | Given the substantial health and economic burden associated with hypertension worldwide, these findings suggest that twice-daily peppermint supplementation may represent a simple, low-cost, and well-tolerated strategy to support blood pressure reduction in this population. | 2 | Sinclair J (2026) | Effects of peppermint (Mentha x piperita L.) oil on cardiometabolic outcomes in patients with pre- and stage 1 hypertension: A placebo randomized controlled trial. |
| Vitamin D Sleep Quality Randomized Trial | Pharmaceutical management is habitually adopted; although its long-term effectiveness remains ambiguous, and accompanying adverse effects are disquieting. | 2 | Sinclair J (2026) | Effects of peppermint (Mentha x piperita L.) oil on cardiometabolic outcomes in patients with pre- and stage 1 hypertension: A placebo randomized controlled trial. |
Source documents