sleep

Glycine

Non-essential amino acid that cools core body temperature and deepens slow-wave sleep — remarkably safe and cheap.

Dosage

Recommended

3 g before bed

Upper limit

30 g/day (well tolerated)

Key Benefits

  • 01Reduces core body temperature to initiate sleep
  • 02Improves sleep quality without drowsiness
  • 03Supports collagen synthesis
  • 04Mildly antidepressant via NMDA modulation
  • 05Reduces daytime sleepiness after poor sleep

Available Forms

Powder (cheapest, mixes well)Capsules

Safety Notes

  • —Clozapine (theoretical — NMDA)
  • —Minimal interactions known

This reference is for informational purposes only. Consult a qualified healthcare provider before starting any supplement.

Learn next

More evidence on Glycine

GuideGlycine Sleep Onset Meta-analysis: What the Evidence SaysGlycine Sleep Onset Meta-analysis has 2 source documents in the current Migaku evidence database...GuideGlycine Sleep And Stress Randomized Trial: What the Evidence SaysGlycine Sleep And Stress Randomized Trial has 2 source documents in the current Migaku evidence...GuideGlycine Temperature Sleep Randomized Trial: What the Evidence SaysGlycine Temperature Sleep Randomized Trial has 2 source documents in the current Migaku evidence...GuideGlycine Sleep Quality Meta-analysis: What the Evidence SaysGlycine Sleep Quality Meta-analysis has 2 source documents in the current Migaku evidence databa...CompareCoenzyme Q10 (Ubiquinone) vs UbiquinolUbiquinone is the traditional, oxidized form of CoQ10. Ubiquinol is the fully reduced, active an...AnswerDoes Glycine Sleep Onset Meta-Analysis work?Glycine Sleep Onset Meta-Analysis has evidence relevant to strength of evidence and what the stu...AnswerIs Glycine Sleep Onset Meta-Analysis safe?Glycine Sleep Onset Meta-Analysis has evidence relevant to safety, limits, and clinician-discuss...AnswerWhat does the evidence say about Glycine Sleep Onset Meta-Analysis?Glycine Sleep Onset Meta-Analysis has evidence relevant to benefits, uncertainty, and practical...
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