topicVitamin D Sleep Meta-Analysis
claimTherefore, the aim of this study was to investigate the association between vitamin D deficiency and the risk of patients receiving a diagnosis of OSA or utilizing CPAP, using the TriNetX research network to obtain real-world data.
evidence level1
citationChiang JK (2026)
sourceVitamin D Deficiency Is Associated with a Higher 5-Year Risk of Obstructive Sleep Apnea and CPAP Use in Older Adults: An Anchor-Based Network Meta-Analysis.
topicVitamin D Sleep Meta-Analysis
claimMaterials and Methods : A retrospective cohort study using the TriNetX database was conducted to investigate the relationship between vitamin D deficiency and patients with risk of receiving an OSA diagnosis or patients treated with CPAP in older adults (≥65 years).
evidence level1
citationChiang JK (2026)
sourceVitamin D Deficiency Is Associated with a Higher 5-Year Risk of Obstructive Sleep Apnea and CPAP Use in Older Adults: An Anchor-Based Network Meta-Analysis.
topicVitamin D Sleep Meta-Analysis
claimAn anchor-based network meta-analysis was also performed to integrate direct and indirect evidence across groups.
evidence level1
citationChiang JK (2026)
sourceVitamin D Deficiency Is Associated with a Higher 5-Year Risk of Obstructive Sleep Apnea and CPAP Use in Older Adults: An Anchor-Based Network Meta-Analysis.
topicVitamin D Sleep Meta-Analysis
claimBackground and Objectives : Continuous positive airway pressure (CPAP) is the standard first-line treatment for patients with obstructive sleep apnea (OSA).
evidence level1
citationChiang JK (2026)
sourceVitamin D Deficiency Is Associated with a Higher 5-Year Risk of Obstructive Sleep Apnea and CPAP Use in Older Adults: An Anchor-Based Network Meta-Analysis.
topicVitamin D Sleep Meta-Analysis
claim3 4 5 6 7 8 8 9 10 10 11 Circadian misalignment has been unequivocally recognized as a risk factor for cardiometabolic diseases.
evidence level3
citationVesković Milena (2026)
sourceVitamin D as a Regulator of the Biological Clock—Implications for Circadian–Metabolic Dysregulation
topicVitamin D Sleep Meta-Analysis
claimInadequate sleep increases the risk of insulin resistance and metabolic syndrome; hence their co-appearance led to the designation of circadian syndrome [,].
evidence level3
citationVesković Milena (2026)
sourceVitamin D as a Regulator of the Biological Clock—Implications for Circadian–Metabolic Dysregulation
topicVitamin D Sleep Meta-Analysis
claimwho actually expanded the cluster of cardiometabolic risk factors to include sleep disturbances and depression [,].
evidence level3
citationVesković Milena (2026)
sourceVitamin D as a Regulator of the Biological Clock—Implications for Circadian–Metabolic Dysregulation
topicVitamin D Sleep Meta-Analysis
claim1 2 Circadian disruption represents a global health problem in the 21st century affecting the majority of the world population.
evidence level3
citationVesković Milena (2026)
sourceVitamin D as a Regulator of the Biological Clock—Implications for Circadian–Metabolic Dysregulation