evidence table
Vitamin D Muscle Function Randomized Trial Evidence Table
Structured evidence table for Vitamin D Muscle Function Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Vitamin D Muscle Function Randomized Trial | Effect of active vitamin D supplementation on muscle mass and function in peritoneal dialysis patients with sarcopenia: a randomized controlled trial. | 2 | Wang L (2026) | Effect of active vitamin D supplementation on muscle mass and function in peritoneal dialysis patients with sarcopenia: a randomized controlled trial. |
| Vitamin D Muscle Function Randomized Trial | Supported by this biological plausibility and by observational studies demonstrating a robust inverse association between serum 25-hydroxyvitamin D (25(OH)D) levels and the risk of fractures and falls, the medical community has witnessed a global surge in vitamin D screening and empiric supplementation over the past two decades []. | 3 | Kong Sung Hye (2026) | Revisiting the Role of Vitamin D in Fracture Prevention in the Era of Mega-Trials |
| Vitamin D Muscle Function Randomized Trial | Furthermore, updated systematic reviews and meta-analyses published in 2025 have reinforced the conclusion that vitamin D supplementation does not reduce fall risk among community-dwelling older adults, with some analyses even suggesting potential harm at higher doses [-]. | 3 | Kong Sung Hye (2026) | Revisiting the Role of Vitamin D in Fracture Prevention in the Era of Mega-Trials |
| Vitamin D Muscle Function Randomized Trial | Most notably, the 2024 Endocrine Society Clinical Practice Guideline now recommends against empiric vitamin D supplementation in healthy adults younger than 75 years, signaling a decisive transition from universal screening toward a more targeted, risk-based approach []. | 3 | Kong Sung Hye (2026) | Revisiting the Role of Vitamin D in Fracture Prevention in the Era of Mega-Trials |
| Vitamin D Muscle Function Randomized Trial | 1 2 3 Vitamin D, often termed the ‘sunshine hormone,’ has been a cornerstone of musculoskeletal preventive medicine for decades. | 3 | Kong Sung Hye (2026) | Revisiting the Role of Vitamin D in Fracture Prevention in the Era of Mega-Trials |
Source documents