Structured evidence table for Vitamin D Hair Loss Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Vitamin D Hair Loss Randomized Trial | Background/objectives Sensorineural hearing loss (SNHL) is a chronic condition with no established pharmacological treatment. | 3 | Mavandi M (2026) | Pharmacotherapeutic Interventions for Sensorineural Hearing Loss: A Scoping Review. |
| Vitamin D Hair Loss Randomized Trial | Recent advances in drug-based therapies offer promising opportunities to prevent or treat SNHL. | 3 | Mavandi M (2026) | Pharmacotherapeutic Interventions for Sensorineural Hearing Loss: A Scoping Review. |
| Vitamin D Hair Loss Randomized Trial | Multiple observational studies have demonstrated that serum 25-hydroxyvitamin D levels are significantly lower in SSNHL patients than in healthy controls, with deficiency associated with greater hearing impairment, poorer treatment response, and higher recurrence risk. | 3 | Wang Y (2026) | Vitamin D and sudden sensorineural hearing loss: emerging associations, mechanistic insights, and prospects for precision medicine - a review. |
| Vitamin D Hair Loss Randomized Trial | However, it must be emphasized that no standardized serum threshold, population-specific validation, or universally accepted predictive model currently exists; therefore, serum 25(OH)D should be regarded as a candidate-rather than an established-biomarker for SSNHL risk stratification. | 3 | Wang Y (2026) | Vitamin D and sudden sensorineural hearing loss: emerging associations, mechanistic insights, and prospects for precision medicine - a review. |
| Vitamin D Hair Loss Randomized Trial | Sudden sensorineural hearing loss (SSNHL) is defined as a rapid hearing decline of ≥30 dB across at least three contiguous frequencies within 72 h, with a multifactorial etiology encompassing vascular, viral, autoimmune, and metabolic mechanisms. | 3 | Wang Y (2026) | Vitamin D and sudden sensorineural hearing loss: emerging associations, mechanistic insights, and prospects for precision medicine - a review. |
| Vitamin D Hair Loss Randomized Trial | Beyond its classical role in calcium and phosphorus homeostasis, vitamin D exerts broad biological effects, including immunomodulation, antioxidant defense, endothelial protection, and neuroprotection, which may collectively preserve inner ear function. | 3 | Wang Y (2026) | Vitamin D and sudden sensorineural hearing loss: emerging associations, mechanistic insights, and prospects for precision medicine - a review. |
Source documents