topicVitamin D Falls Meta-Analysis
claimRisk ratios (RRs) with 95% confidence intervals (CIs) were calculated, using random-effects meta-analysis where appropriate.
evidence level1
citationAlalwani YJ (2026)
sourceFall Prevention Interventions and Fracture Risk in Community-Dwelling Older Adults: A Systematic Review and Meta-Analysis.
topicVitamin D Falls Meta-Analysis
claimConclusions: Current evidence suggests fall prevention interventions may reduce hip fractures but do not significantly prevent fractures overall.
evidence level1
citationAlalwani YJ (2026)
sourceFall Prevention Interventions and Fracture Risk in Community-Dwelling Older Adults: A Systematic Review and Meta-Analysis.
topicVitamin D Falls Meta-Analysis
claimDespite consistent fall reduction, the translation to fracture prevention remains uncertain, highlighting the need for integrated interventions targeting both fall risk and bone health.
evidence level1
citationAlalwani YJ (2026)
sourceFall Prevention Interventions and Fracture Risk in Community-Dwelling Older Adults: A Systematic Review and Meta-Analysis.
topicVitamin D Falls Meta-Analysis
claimIntroduction: Falls and subsequent fractures represent a major public health concern among older adults.
evidence level1
citationAlalwani YJ (2026)
sourceFall Prevention Interventions and Fracture Risk in Community-Dwelling Older Adults: A Systematic Review and Meta-Analysis.
topicVitamin D Falls Meta-Analysis
claimSupported by this biological plausibility and by observational studies demonstrating a robust inverse association between serum 25-hydroxyvitamin D (25(OH)D) levels and the risk of fractures and falls, the medical community has witnessed a global surge in vitamin D screening and empiric supplementation over the past two decades [].
evidence level3
citationKong Sung Hye (2026)
sourceRevisiting the Role of Vitamin D in Fracture Prevention in the Era of Mega-Trials
topicVitamin D Falls Meta-Analysis
claimFurthermore, updated systematic reviews and meta-analyses published in 2025 have reinforced the conclusion that vitamin D supplementation does not reduce fall risk among community-dwelling older adults, with some analyses even suggesting potential harm at higher doses [-].
evidence level3
citationKong Sung Hye (2026)
sourceRevisiting the Role of Vitamin D in Fracture Prevention in the Era of Mega-Trials
topicVitamin D Falls Meta-Analysis
claimMost notably, the 2024 Endocrine Society Clinical Practice Guideline now recommends against empiric vitamin D supplementation in healthy adults younger than 75 years, signaling a decisive transition from universal screening toward a more targeted, risk-based approach [].
evidence level3
citationKong Sung Hye (2026)
sourceRevisiting the Role of Vitamin D in Fracture Prevention in the Era of Mega-Trials
topicVitamin D Falls Meta-Analysis
claim1 2 3 Vitamin D, often termed the ‘sunshine hormone,’ has been a cornerstone of musculoskeletal preventive medicine for decades.
evidence level3
citationKong Sung Hye (2026)
sourceRevisiting the Role of Vitamin D in Fracture Prevention in the Era of Mega-Trials