evidence table

Vitamin D Deficiency Guideline Evidence Table

Structured evidence table for Vitamin D Deficiency Guideline, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Vitamin D Deficiency GuidelineSupported by this biological plausibility and by observational studies demonstrating a robust inverse association between serum 25-hydroxyvitamin D (25(OH)D) levels and the risk of fractures and falls, the medical community has witnessed a global surge in vitamin D screening and empiric supplementation over the past two decades [].3Kong Sung Hye (2026)Revisiting the Role of Vitamin D in Fracture Prevention in the Era of Mega-Trials
Vitamin D Deficiency GuidelineFurthermore, updated systematic reviews and meta-analyses published in 2025 have reinforced the conclusion that vitamin D supplementation does not reduce fall risk among community-dwelling older adults, with some analyses even suggesting potential harm at higher doses [-].3Kong Sung Hye (2026)Revisiting the Role of Vitamin D in Fracture Prevention in the Era of Mega-Trials
Vitamin D Deficiency GuidelineMost notably, the 2024 Endocrine Society Clinical Practice Guideline now recommends against empiric vitamin D supplementation in healthy adults younger than 75 years, signaling a decisive transition from universal screening toward a more targeted, risk-based approach [].3Kong Sung Hye (2026)Revisiting the Role of Vitamin D in Fracture Prevention in the Era of Mega-Trials
Vitamin D Deficiency Guideline1 2 3 Vitamin D, often termed the ‘sunshine hormone,’ has been a cornerstone of musculoskeletal preventive medicine for decades.3Kong Sung Hye (2026)Revisiting the Role of Vitamin D in Fracture Prevention in the Era of Mega-Trials
Vitamin D Deficiency GuidelineBeyond a Universal Threshold: Reconsidering the Clinical Meaning of Vitamin D Insufficiency.4Kim KJ (2026)Beyond a Universal Threshold: Reconsidering the Clinical Meaning of Vitamin D Insufficiency.
topicVitamin D Deficiency Guideline
claimSupported by this biological plausibility and by observational studies demonstrating a robust inverse association between serum 25-hydroxyvitamin D (25(OH)D) levels and the risk of fractures and falls, the medical community has witnessed a global surge in vitamin D screening and empiric supplementation over the past two decades [].
evidence level3
citationKong Sung Hye (2026)
sourceRevisiting the Role of Vitamin D in Fracture Prevention in the Era of Mega-Trials
topicVitamin D Deficiency Guideline
claimFurthermore, updated systematic reviews and meta-analyses published in 2025 have reinforced the conclusion that vitamin D supplementation does not reduce fall risk among community-dwelling older adults, with some analyses even suggesting potential harm at higher doses [-].
evidence level3
citationKong Sung Hye (2026)
sourceRevisiting the Role of Vitamin D in Fracture Prevention in the Era of Mega-Trials
topicVitamin D Deficiency Guideline
claimMost notably, the 2024 Endocrine Society Clinical Practice Guideline now recommends against empiric vitamin D supplementation in healthy adults younger than 75 years, signaling a decisive transition from universal screening toward a more targeted, risk-based approach [].
evidence level3
citationKong Sung Hye (2026)
sourceRevisiting the Role of Vitamin D in Fracture Prevention in the Era of Mega-Trials
topicVitamin D Deficiency Guideline
claim1 2 3 Vitamin D, often termed the ‘sunshine hormone,’ has been a cornerstone of musculoskeletal preventive medicine for decades.
evidence level3
citationKong Sung Hye (2026)
sourceRevisiting the Role of Vitamin D in Fracture Prevention in the Era of Mega-Trials
topicVitamin D Deficiency Guideline
claimBeyond a Universal Threshold: Reconsidering the Clinical Meaning of Vitamin D Insufficiency.
evidence level4
citationKim KJ (2026)
sourceBeyond a Universal Threshold: Reconsidering the Clinical Meaning of Vitamin D Insufficiency.

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Source documents

  1. Revisiting the Role of Vitamin D in Fracture Prevention in the Era of Mega-Trials
  2. Beyond a Universal Threshold: Reconsidering the Clinical Meaning of Vitamin D Insufficiency.