Vitamin D Bone Density Meta-Analysis Evidence Table

Structured evidence table for Vitamin D Bone Density Meta-Analysis, generated from 4 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Vitamin D Bone Density Meta-AnalysisThis systematic review and meta-analysis aim to investigate the association between DASH diet and risk of osteoporosis and fracture.1Yang B (2026)Association of Dietary Approaches to Stop Hypertension Diet With the Risk of Osteoporosis and Fracture: A Systematic Review and Meta-Analysis.
Vitamin D Bone Density Meta-AnalysisTwo authors performed data extraction independently and assessed the risk of bias.1Yang B (2026)Association of Dietary Approaches to Stop Hypertension Diet With the Risk of Osteoporosis and Fracture: A Systematic Review and Meta-Analysis.
Vitamin D Bone Density Meta-AnalysisOverall, adherence to DASH diet was not significantly associated with bone health.1Yang B (2026)Association of Dietary Approaches to Stop Hypertension Diet With the Risk of Osteoporosis and Fracture: A Systematic Review and Meta-Analysis.
Vitamin D Bone Density Meta-AnalysisA comprehensive literature search was conducted in PubMed, Ovid Embase, Scopus, Web of Science Core Collection and Ovid Medline databases from inception to September 2024.1Yang B (2026)Association of Dietary Approaches to Stop Hypertension Diet With the Risk of Osteoporosis and Fracture: A Systematic Review and Meta-Analysis.
Vitamin D Bone Density Meta-AnalysisThe worldwide health organization considers osteoporosis and its associated fragile bone breaks to be two of the most serious public health issues because they affect more than 200 million people who have osteoporosis according to its estimates and women and men above 50 years of age face a lifetime fracture risk that exceeds 50 percent and 20 percent, respectively ().1Lv Chen (2026)Effects of macro- and micronutrient intake on bone mineral density, osteoporotic fracture risk, inflammation, and functional rehabilitation outcomes in orthopedic patients: a systematic review and meta-analysis
Vitamin D Bone Density Meta-AnalysisThe economic costs which result from fracture-related health problems create a significant financial burden while they result in extended periods of disability and independence loss and they increase the risk of death which demonstrates that society needs to develop better methods for both preventing and treating these conditions ().1Lv Chen (2026)Effects of macro- and micronutrient intake on bone mineral density, osteoporotic fracture risk, inflammation, and functional rehabilitation outcomes in orthopedic patients: a systematic review and meta-analysis
Vitamin D Bone Density Meta-AnalysisIncreased levels of the inflammatory cytokines TNF-and IL-6 and CRP lead to faster bone loss and slower bone healing and more difficulties after surgery.1Lv Chen (2026)Effects of macro- and micronutrient intake on bone mineral density, osteoporotic fracture risk, inflammation, and functional rehabilitation outcomes in orthopedic patients: a systematic review and meta-analysis
Vitamin D Bone Density Meta-Analysis1 2 3–5 Bone health serves as the essential factor that determines how musculoskeletal systems operate and how much people enjoy their lives and how often they experience health problems in particular for elderly individuals and people with orthopedic conditions.1Lv Chen (2026)Effects of macro- and micronutrient intake on bone mineral density, osteoporotic fracture risk, inflammation, and functional rehabilitation outcomes in orthopedic patients: a systematic review and meta-analysis
Vitamin D Bone Density Meta-AnalysisHigh‐quality meta‐analyses of randomized clinical trials (RCT) found that vitamin D supplementation would help increase the BMD in the femur neck area but not at other sites (Reid et al. ).3Zeng Hualian (2026)The Impact of Serum 25‐Hydroxyvitamin D on Bone Mineral Density at Different Skeletal Sites: A Multivariate Analysis Based on a UK Cohort Study
Vitamin D Bone Density Meta-AnalysisFurthermore, large‐scale trials, such as the VITAL trial, have demonstrated that supplemental vitamin D3 (2000 IU/day) did not result in significant bone density changes compared to placebo at the spine, hip, or total body in generally healthy adults (LeBoff et al. ).3Zeng Hualian (2026)The Impact of Serum 25‐Hydroxyvitamin D on Bone Mineral Density at Different Skeletal Sites: A Multivariate Analysis Based on a UK Cohort Study
Vitamin D Bone Density Meta-Analysis2004 2023 2020 2011 2023 2012 2014 2020 2018 Several observational studies with cross‐sectional or case–control designs found serum vitamin D is associated with individual sites of BMD in the upper limb, femur, and spine (Bischoff‐Ferrari et al. ; Khodabakhshi et al. ; Liu et al. ; Øyen et al. ; Wang and Yang ).3Zeng Hualian (2026)The Impact of Serum 25‐Hydroxyvitamin D on Bone Mineral Density at Different Skeletal Sites: A Multivariate Analysis Based on a UK Cohort Study
Vitamin D Bone Density Meta-Analysis2011 2019 2022 2021 Low bone mineral density (BMD) is the primary clinical manifestation and diagnostic variable of osteoporosis, a chronic disorder characterized by bone mass reduction and bone microarchitecture deterioration (Rachner et al. ).3Zeng Hualian (2026)The Impact of Serum 25‐Hydroxyvitamin D on Bone Mineral Density at Different Skeletal Sites: A Multivariate Analysis Based on a UK Cohort Study
topicVitamin D Bone Density Meta-Analysis
claimThis systematic review and meta-analysis aim to investigate the association between DASH diet and risk of osteoporosis and fracture.
evidence level1
citationYang B (2026)
sourceAssociation of Dietary Approaches to Stop Hypertension Diet With the Risk of Osteoporosis and Fracture: A Systematic Review and Meta-Analysis.
topicVitamin D Bone Density Meta-Analysis
claimTwo authors performed data extraction independently and assessed the risk of bias.
evidence level1
citationYang B (2026)
sourceAssociation of Dietary Approaches to Stop Hypertension Diet With the Risk of Osteoporosis and Fracture: A Systematic Review and Meta-Analysis.
topicVitamin D Bone Density Meta-Analysis
claimOverall, adherence to DASH diet was not significantly associated with bone health.
evidence level1
citationYang B (2026)
sourceAssociation of Dietary Approaches to Stop Hypertension Diet With the Risk of Osteoporosis and Fracture: A Systematic Review and Meta-Analysis.
topicVitamin D Bone Density Meta-Analysis
claimA comprehensive literature search was conducted in PubMed, Ovid Embase, Scopus, Web of Science Core Collection and Ovid Medline databases from inception to September 2024.
evidence level1
citationYang B (2026)
sourceAssociation of Dietary Approaches to Stop Hypertension Diet With the Risk of Osteoporosis and Fracture: A Systematic Review and Meta-Analysis.
topicVitamin D Bone Density Meta-Analysis
claimThe worldwide health organization considers osteoporosis and its associated fragile bone breaks to be two of the most serious public health issues because they affect more than 200 million people who have osteoporosis according to its estimates and women and men above 50 years of age face a lifetime fracture risk that exceeds 50 percent and 20 percent, respectively ().
evidence level1
citationLv Chen (2026)
sourceEffects of macro- and micronutrient intake on bone mineral density, osteoporotic fracture risk, inflammation, and functional rehabilitation outcomes in orthopedic patients: a systematic review and meta-analysis
topicVitamin D Bone Density Meta-Analysis
claimThe economic costs which result from fracture-related health problems create a significant financial burden while they result in extended periods of disability and independence loss and they increase the risk of death which demonstrates that society needs to develop better methods for both preventing and treating these conditions ().
evidence level1
citationLv Chen (2026)
sourceEffects of macro- and micronutrient intake on bone mineral density, osteoporotic fracture risk, inflammation, and functional rehabilitation outcomes in orthopedic patients: a systematic review and meta-analysis
topicVitamin D Bone Density Meta-Analysis
claimIncreased levels of the inflammatory cytokines TNF-and IL-6 and CRP lead to faster bone loss and slower bone healing and more difficulties after surgery.
evidence level1
citationLv Chen (2026)
sourceEffects of macro- and micronutrient intake on bone mineral density, osteoporotic fracture risk, inflammation, and functional rehabilitation outcomes in orthopedic patients: a systematic review and meta-analysis
topicVitamin D Bone Density Meta-Analysis
claim1 2 3–5 Bone health serves as the essential factor that determines how musculoskeletal systems operate and how much people enjoy their lives and how often they experience health problems in particular for elderly individuals and people with orthopedic conditions.
evidence level1
citationLv Chen (2026)
sourceEffects of macro- and micronutrient intake on bone mineral density, osteoporotic fracture risk, inflammation, and functional rehabilitation outcomes in orthopedic patients: a systematic review and meta-analysis
topicVitamin D Bone Density Meta-Analysis
claimHigh‐quality meta‐analyses of randomized clinical trials (RCT) found that vitamin D supplementation would help increase the BMD in the femur neck area but not at other sites (Reid et al. ).
evidence level3
citationZeng Hualian (2026)
sourceThe Impact of Serum 25‐Hydroxyvitamin D on Bone Mineral Density at Different Skeletal Sites: A Multivariate Analysis Based on a UK Cohort Study
topicVitamin D Bone Density Meta-Analysis
claimFurthermore, large‐scale trials, such as the VITAL trial, have demonstrated that supplemental vitamin D3 (2000 IU/day) did not result in significant bone density changes compared to placebo at the spine, hip, or total body in generally healthy adults (LeBoff et al. ).
evidence level3
citationZeng Hualian (2026)
sourceThe Impact of Serum 25‐Hydroxyvitamin D on Bone Mineral Density at Different Skeletal Sites: A Multivariate Analysis Based on a UK Cohort Study
topicVitamin D Bone Density Meta-Analysis
claim2004 2023 2020 2011 2023 2012 2014 2020 2018 Several observational studies with cross‐sectional or case–control designs found serum vitamin D is associated with individual sites of BMD in the upper limb, femur, and spine (Bischoff‐Ferrari et al. ; Khodabakhshi et al. ; Liu et al. ; Øyen et al. ; Wang and Yang ).
evidence level3
citationZeng Hualian (2026)
sourceThe Impact of Serum 25‐Hydroxyvitamin D on Bone Mineral Density at Different Skeletal Sites: A Multivariate Analysis Based on a UK Cohort Study
topicVitamin D Bone Density Meta-Analysis
claim2011 2019 2022 2021 Low bone mineral density (BMD) is the primary clinical manifestation and diagnostic variable of osteoporosis, a chronic disorder characterized by bone mass reduction and bone microarchitecture deterioration (Rachner et al. ).
evidence level3
citationZeng Hualian (2026)
sourceThe Impact of Serum 25‐Hydroxyvitamin D on Bone Mineral Density at Different Skeletal Sites: A Multivariate Analysis Based on a UK Cohort Study

Source documents

  1. Association of Dietary Approaches to Stop Hypertension Diet With the Risk of Osteoporosis and Fracture: A Systematic Review and Meta-Analysis.
  2. Effects of macro- and micronutrient intake on bone mineral density, osteoporotic fracture risk, inflammation, and functional rehabilitation outcomes in orthopedic patients: a systematic review and meta-analysis
  3. The Impact of Serum 25‐Hydroxyvitamin D on Bone Mineral Density at Different Skeletal Sites: A Multivariate Analysis Based on a UK Cohort Study
  4. Editorial: Vitamin D and aging: associations with mortality, cognition, chronic diseases, and metabolic conditions in elderly individuals.