topicVitamin C Immune Support Randomized Trial
claimResults We found no significant difference in GVHD occurrence and levels of retinoids between the intervention and control groups at either of the two time points.
evidence level2
citationIversen PO (2026)
sourcePlasma Levels of Retinoids and Carotenoids in Recipients of Allogeneic Hematopoietic Stem Cell Transplantation Given Extracorporeal Photopheresis to Prevent Graft-Versus-Host Disease-Analyses From a Randomized Trial.
topicVitamin C Immune Support Randomized Trial
claimConclusion Whether routine vitamin A supplementation is warranted for GVHD prevention, needs further study.
evidence level2
citationIversen PO (2026)
sourcePlasma Levels of Retinoids and Carotenoids in Recipients of Allogeneic Hematopoietic Stem Cell Transplantation Given Extracorporeal Photopheresis to Prevent Graft-Versus-Host Disease-Analyses From a Randomized Trial.
topicVitamin C Immune Support Randomized Trial
claimIntroduction Whether retinoids and carotenoids impact on graft-versus-host disease (GVHD) following allogeneic stem cell transplantation (ASCT) is unknown.
evidence level2
citationIversen PO (2026)
sourcePlasma Levels of Retinoids and Carotenoids in Recipients of Allogeneic Hematopoietic Stem Cell Transplantation Given Extracorporeal Photopheresis to Prevent Graft-Versus-Host Disease-Analyses From a Randomized Trial.
topicVitamin C Immune Support Randomized Trial
claimMethods We conducted a 1:1 randomized controlled trial with extracorporeal photopheresis for GVHD-prophylaxis as the intervention.
evidence level2
citationIversen PO (2026)
sourcePlasma Levels of Retinoids and Carotenoids in Recipients of Allogeneic Hematopoietic Stem Cell Transplantation Given Extracorporeal Photopheresis to Prevent Graft-Versus-Host Disease-Analyses From a Randomized Trial.
topicVitamin C Immune Support Randomized Trial
claimResistance often develops through genetic changes in fungi, such as mutations in drug targets or increased drug efflux.
evidence level3
citationAkimbekov Nuraly S. (2026)
sourceVitamin D–AMP axis in host defense against fungal infections
topicVitamin C Immune Support Randomized Trial
claimThis growing problem poses a serious challenge to public health, limiting treatment options and increasing the risk of adverse outcomes for patients, particularly those with invasive candidiasis and mold disease ().
evidence level3
citationAkimbekov Nuraly S. (2026)
sourceVitamin D–AMP axis in host defense against fungal infections
topicVitamin C Immune Support Randomized Trial
claimGrowing evidence suggests that vitamin D increases innate immunity by regulating the production of AMPs ().
evidence level3
citationAkimbekov Nuraly S. (2026)
sourceVitamin D–AMP axis in host defense against fungal infections
topicVitamin C Immune Support Randomized Trial
claimThis trend is concerning, as it is coupled with the emergence of drug-resistant fungal strains and limited treatment options, leading to a substantial global health burden ().
evidence level3
citationAkimbekov Nuraly S. (2026)
sourceVitamin D–AMP axis in host defense against fungal infections