Structured evidence table for Vitamin C Common Cold Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Vitamin C Common Cold Randomized Trial | This UK level was based on the 1953 Sheffield study, which found that 10 mg/d prevents scurvy, with 40 mg/d chosen as the recommended level for yielding somewhat higher plasma levels. | 2 | Hemilä H (2025) | Are the UK's vitamin C recommendations evidence-based? A critical comment. |
| Vitamin C Common Cold Randomized Trial | In this commentary, we argue that the UK recommendation overlooked key evidence available at the time. | 2 | Hemilä H (2025) | Are the UK's vitamin C recommendations evidence-based? A critical comment. |
| Vitamin C Common Cold Randomized Trial | One randomised controlled trial, published in 1993, found benefits from vitamin C supplementation even at a baseline intake of about 500 mg/d; however, this trial involved ultramarathon runners, and the findings should not be broadly generalised. | 2 | Hemilä H (2025) | Are the UK's vitamin C recommendations evidence-based? A critical comment. |
| Vitamin C Common Cold Randomized Trial | There is substantial international variation in recommended vitamin C intake levels. | 2 | Hemilä H (2025) | Are the UK's vitamin C recommendations evidence-based? A critical comment. |
| Vitamin C Common Cold Randomized Trial | As a result, common infections are becoming harder to treat, leading to prolonged illness, increased healthcare costs, higher mortality, and a growing burden on healthcare systems worldwide [,]. | 4 | Alexandrova Alexandra S. (2026) | A Review of the Properties of Clinically Evaluated Plant-Derived Agents in the Treatment of Respiratory Infections |
| Vitamin C Common Cold Randomized Trial | Clinical decisions should be based on the quality of available evidence, safety considerations, and the individual characteristics of each patient [,,]. | 4 | Alexandrova Alexandra S. (2026) | A Review of the Properties of Clinically Evaluated Plant-Derived Agents in the Treatment of Respiratory Infections |
| Vitamin C Common Cold Randomized Trial | The use of evidence-based herbal products for symptomatic relief can help reduce inappropriate antibiotic prescribing and self-medication. | 4 | Alexandrova Alexandra S. (2026) | A Review of the Properties of Clinically Evaluated Plant-Derived Agents in the Treatment of Respiratory Infections |
| Vitamin C Common Cold Randomized Trial | 1 2 3 4 5 6 7 8 Upper and lower respiratory tract infections (URTIs and LRTIs) are prevalent health concerns globally, accounting for a significant burden of illness and healthcare resources. | 4 | Alexandrova Alexandra S. (2026) | A Review of the Properties of Clinically Evaluated Plant-Derived Agents in the Treatment of Respiratory Infections |
Source documents