topicVitamin C Cold Randomized Trial
claim1 2 3 4 5 6 7 8 9 10 11 12 10 13 14 Immune system aging is a cause of increased morbidity and mortality among older adults.
evidence level4
citationCąkała-Jakimowicz Marta (2026)
sourceA Healthy Lifestyle Can Slow Immune System Aging and Reduce Age-Related Chronic Inflammation: A Narrative Review
topicVitamin C Cold Randomized Trial
claimImmunoaging combined with unfavorable environmental influences and an inappropriate lifestyle (environmental pollution, poor dietary habits, lack of physical activity, occupational stress, etc.) is associated with the development and progression of age-related diseases [].
evidence level4
citationCąkała-Jakimowicz Marta (2026)
sourceA Healthy Lifestyle Can Slow Immune System Aging and Reduce Age-Related Chronic Inflammation: A Narrative Review
topicVitamin C Cold Randomized Trial
claimThe process of cellular aging is associated with the accumulation of DNA damage, telomere shortening, epigenetic drift, loss of proteostasis, mitochondrial dysfunction, and impaired intercellular communication [], leading to persistent cell cycle arrest, morphological, metabolic, and functional abnormalities, and relative resistance to apoptosis [,].
evidence level4
citationCąkała-Jakimowicz Marta (2026)
sourceA Healthy Lifestyle Can Slow Immune System Aging and Reduce Age-Related Chronic Inflammation: A Narrative Review
topicVitamin C Cold Randomized Trial
claimImmunoaging involves the involution of lymphatic organs and senescence of immune cells (immunosenescence).
evidence level4
citationCąkała-Jakimowicz Marta (2026)
sourceA Healthy Lifestyle Can Slow Immune System Aging and Reduce Age-Related Chronic Inflammation: A Narrative Review
topicVitamin C Cold Randomized Trial
claimAs a result, common infections are becoming harder to treat, leading to prolonged illness, increased healthcare costs, higher mortality, and a growing burden on healthcare systems worldwide [,].
evidence level4
citationAlexandrova Alexandra S. (2026)
sourceA Review of the Properties of Clinically Evaluated Plant-Derived Agents in the Treatment of Respiratory Infections
topicVitamin C Cold Randomized Trial
claimClinical decisions should be based on the quality of available evidence, safety considerations, and the individual characteristics of each patient [,,].
evidence level4
citationAlexandrova Alexandra S. (2026)
sourceA Review of the Properties of Clinically Evaluated Plant-Derived Agents in the Treatment of Respiratory Infections
topicVitamin C Cold Randomized Trial
claimThe use of evidence-based herbal products for symptomatic relief can help reduce inappropriate antibiotic prescribing and self-medication.
evidence level4
citationAlexandrova Alexandra S. (2026)
sourceA Review of the Properties of Clinically Evaluated Plant-Derived Agents in the Treatment of Respiratory Infections
topicVitamin C Cold Randomized Trial
claim1 2 3 4 5 6 7 8 Upper and lower respiratory tract infections (URTIs and LRTIs) are prevalent health concerns globally, accounting for a significant burden of illness and healthcare resources.
evidence level4
citationAlexandrova Alexandra S. (2026)
sourceA Review of the Properties of Clinically Evaluated Plant-Derived Agents in the Treatment of Respiratory Infections