topicVitamin B6 PMS Randomized Trial
claimMoreover, taking such drugs during Ramadan has been reported to increase the risk of cerebral venous thrombosis [], and psychological resistance remains a major global challenge [].
evidence level2
citationIimura Jun (2026)
sourceNovel dietary FemTech based on dietary reference intakes for premenstrual and menstrual disorders: a pilot open-label randomized controlled trial of dietary intervention
topicVitamin B6 PMS Randomized Trial
claimFor instance, Ahmadi reported that zinc supplementation reduced PMD symptoms [], and Tartagni reported the same for vitamin D [].
evidence level2
citationIimura Jun (2026)
sourceNovel dietary FemTech based on dietary reference intakes for premenstrual and menstrual disorders: a pilot open-label randomized controlled trial of dietary intervention
topicVitamin B6 PMS Randomized Trial
claimAs summarized by Carlini, there is insufficient evidence to recommend improvements through interventions with a single nutrient [].
evidence level2
citationIimura Jun (2026)
sourceNovel dietary FemTech based on dietary reference intakes for premenstrual and menstrual disorders: a pilot open-label randomized controlled trial of dietary intervention
topicVitamin B6 PMS Randomized Trial
claim1 2 3 4 5 Premenstrual disorder (PMD) is a serious issue for women across cultures, and is a comprehensive concept encompassing both physical and mental symptoms [].
evidence level2
citationIimura Jun (2026)
sourceNovel dietary FemTech based on dietary reference intakes for premenstrual and menstrual disorders: a pilot open-label randomized controlled trial of dietary intervention
topicVitamin B6 PMS Randomized Trial
claimSome evidence suggests that women with Rh-negative blood type may have a higher likelihood of developing premenstrual symptoms, although mechanistic explanations remain speculative and findings are not yet consistent across studies.
evidence level4
citationMartire Francesco Giuseppe (2026)
sourcePremenstrual Syndrome and Nutritional Factors: A Narrative Review of Current Evidence and Clinical Implications
topicVitamin B6 PMS Randomized Trial
claimHigh caffeine intake has also been linked to increased PMS risk, possibly through its impact on sleep quality, anxiety, and neuroendocrine regulation.
evidence level4
citationMartire Francesco Giuseppe (2026)
sourcePremenstrual Syndrome and Nutritional Factors: A Narrative Review of Current Evidence and Clinical Implications
topicVitamin B6 PMS Randomized Trial
claim13 3 14 15 16 17 18 19 20 13 21 22 23 13 13 3 22 The etiopathogenesis of PMS and PMDD is multifactorial and remains only partially understood, but current evidence indicates that symptoms arise from a complex interplay between normal ovarian steroid fluctuations and an underlying neurobiological vulnerability present only in susceptible individuals.
evidence level4
citationMartire Francesco Giuseppe (2026)
sourcePremenstrual Syndrome and Nutritional Factors: A Narrative Review of Current Evidence and Clinical Implications
topicVitamin B6 PMS Randomized Trial
claim1 2 3 4 5 6 Premenstrual syndrome is a gynaecological and psychiatric disorder that reduces the quality of life of affected patients [].
evidence level4
citationMartire Francesco Giuseppe (2026)
sourcePremenstrual Syndrome and Nutritional Factors: A Narrative Review of Current Evidence and Clinical Implications