Structured evidence table for Vitamin B6 PMS Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Vitamin B6 PMS Meta-Analysis | The quality of the selected articles was assessed utilizing the Cochrane Risk of Bias assessment checklist. | 1 | Sharifipour F (2025) | The effectiveness of vitamin B6 in reducing mastalgia: a systematic review and meta-analysis. |
| Vitamin B6 PMS Meta-Analysis | The combined analysis of these three studies indicated that there were no differences between the two groups of vitamins B6 and placebo in a reduction of pain intensity (SMD = -3.57, 95% CI: -9.15 to 2.01; very low certainty of evidence), with high heterogeneity among the studies (I² = 99.56%). | 1 | Sharifipour F (2025) | The effectiveness of vitamin B6 in reducing mastalgia: a systematic review and meta-analysis. |
| Vitamin B6 PMS Meta-Analysis | Conclusion This meta-analysis did not demonstrate a statistically significant effect of vitamin B6 on mastalgia severity. | 1 | Sharifipour F (2025) | The effectiveness of vitamin B6 in reducing mastalgia: a systematic review and meta-analysis. |
| Vitamin B6 PMS Meta-Analysis | Background Mastalgia represents the most frequent complaint among women at some point during their lives that can have a profound impact on both the physical and mental well-being of individuals affected by this condition. | 1 | Sharifipour F (2025) | The effectiveness of vitamin B6 in reducing mastalgia: a systematic review and meta-analysis. |
| Vitamin B6 PMS Meta-Analysis | Some evidence suggests that women with Rh-negative blood type may have a higher likelihood of developing premenstrual symptoms, although mechanistic explanations remain speculative and findings are not yet consistent across studies. | 4 | Martire Francesco Giuseppe (2026) | Premenstrual Syndrome and Nutritional Factors: A Narrative Review of Current Evidence and Clinical Implications |
| Vitamin B6 PMS Meta-Analysis | High caffeine intake has also been linked to increased PMS risk, possibly through its impact on sleep quality, anxiety, and neuroendocrine regulation. | 4 | Martire Francesco Giuseppe (2026) | Premenstrual Syndrome and Nutritional Factors: A Narrative Review of Current Evidence and Clinical Implications |
| Vitamin B6 PMS Meta-Analysis | 13 3 14 15 16 17 18 19 20 13 21 22 23 13 13 3 22 The etiopathogenesis of PMS and PMDD is multifactorial and remains only partially understood, but current evidence indicates that symptoms arise from a complex interplay between normal ovarian steroid fluctuations and an underlying neurobiological vulnerability present only in susceptible individuals. | 4 | Martire Francesco Giuseppe (2026) | Premenstrual Syndrome and Nutritional Factors: A Narrative Review of Current Evidence and Clinical Implications |
| Vitamin B6 PMS Meta-Analysis | 1 2 3 4 5 6 Premenstrual syndrome is a gynaecological and psychiatric disorder that reduces the quality of life of affected patients []. | 4 | Martire Francesco Giuseppe (2026) | Premenstrual Syndrome and Nutritional Factors: A Narrative Review of Current Evidence and Clinical Implications |
Source documents