Vitamin-B6-Fatigue-Randomized-Trial Evidence Table

Structured evidence table for Vitamin-B6-Fatigue-Randomized-Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Vitamin-B6-Fatigue-Randomized-TrialMethods Building on these findings, we identified candidate nutrients found in foods that could enhance brain GSH production as a possible approach to sustain motivated behaviors.2Anlacan VM (2026)A nutritional blend of taurine, vitamins B6, B9, and B12 improves motivated behaviors in healthy adults-a double-blinded randomized clinical trial.
Vitamin-B6-Fatigue-Randomized-TrialThe blend was also found to reduce the number of lapses during the Psychomotor Vigilance Task after 14 days, but not after 28 days of intake.2Anlacan VM (2026)A nutritional blend of taurine, vitamins B6, B9, and B12 improves motivated behaviors in healthy adults-a double-blinded randomized clinical trial.
Vitamin-B6-Fatigue-Randomized-TrialIntroduction Motivation is a key driver in achieving goals and performing daily tasks, involving cost-benefit valuations of the amount of effort required for a particular reward and can be influenced by socio-environmental factors and neurological conditions that may impact the brain reward circuitry.2Anlacan VM (2026)A nutritional blend of taurine, vitamins B6, B9, and B12 improves motivated behaviors in healthy adults-a double-blinded randomized clinical trial.
Vitamin-B6-Fatigue-Randomized-TrialNotably, research has shown that higher glutathione levels (GSH) in the nucleus accumbens are linked with better and more consistent performance in effortful tasks in both preclinical models and humans.2Anlacan VM (2026)A nutritional blend of taurine, vitamins B6, B9, and B12 improves motivated behaviors in healthy adults-a double-blinded randomized clinical trial.
Vitamin-B6-Fatigue-Randomized-TrialSupplementation with B vitamins and magnesium improved fatigue and symptom-based disease activity scores in UC; however, effects on underlying inflammatory activity remain uncertain.4Ramezani E (2026)Effects of B vitamins and magnesium on fatigue, disease activity and quality of life in inflammatory bowel disease.
Vitamin-B6-Fatigue-Randomized-TrialThis study investigated the efficacy of supplementation with B vitamins and magnesium in alleviating fatigue, improving disease activity, and health-related quality of life (HRQoL) in patients with inflammatory bowel disease (IBD) based on patient-reported outcomes.4Ramezani E (2026)Effects of B vitamins and magnesium on fatigue, disease activity and quality of life in inflammatory bowel disease.
Vitamin-B6-Fatigue-Randomized-TrialIn this randomized, double-blind, placebo-controlled trial, 98 adults with IBD in remission were randomized (1:1) to receive daily supplementation with vitamins B 1 , B 6 , B 12 , and magnesium or a matching placebo for 4 weeks.4Ramezani E (2026)Effects of B vitamins and magnesium on fatigue, disease activity and quality of life in inflammatory bowel disease.
topicVitamin-B6-Fatigue-Randomized-Trial
claimMethods Building on these findings, we identified candidate nutrients found in foods that could enhance brain GSH production as a possible approach to sustain motivated behaviors.
evidence level2
citationAnlacan VM (2026)
sourceA nutritional blend of taurine, vitamins B6, B9, and B12 improves motivated behaviors in healthy adults-a double-blinded randomized clinical trial.
topicVitamin-B6-Fatigue-Randomized-Trial
claimThe blend was also found to reduce the number of lapses during the Psychomotor Vigilance Task after 14 days, but not after 28 days of intake.
evidence level2
citationAnlacan VM (2026)
sourceA nutritional blend of taurine, vitamins B6, B9, and B12 improves motivated behaviors in healthy adults-a double-blinded randomized clinical trial.
topicVitamin-B6-Fatigue-Randomized-Trial
claimIntroduction Motivation is a key driver in achieving goals and performing daily tasks, involving cost-benefit valuations of the amount of effort required for a particular reward and can be influenced by socio-environmental factors and neurological conditions that may impact the brain reward circuitry.
evidence level2
citationAnlacan VM (2026)
sourceA nutritional blend of taurine, vitamins B6, B9, and B12 improves motivated behaviors in healthy adults-a double-blinded randomized clinical trial.
topicVitamin-B6-Fatigue-Randomized-Trial
claimNotably, research has shown that higher glutathione levels (GSH) in the nucleus accumbens are linked with better and more consistent performance in effortful tasks in both preclinical models and humans.
evidence level2
citationAnlacan VM (2026)
sourceA nutritional blend of taurine, vitamins B6, B9, and B12 improves motivated behaviors in healthy adults-a double-blinded randomized clinical trial.
topicVitamin-B6-Fatigue-Randomized-Trial
claimSupplementation with B vitamins and magnesium improved fatigue and symptom-based disease activity scores in UC; however, effects on underlying inflammatory activity remain uncertain.
evidence level4
citationRamezani E (2026)
sourceEffects of B vitamins and magnesium on fatigue, disease activity and quality of life in inflammatory bowel disease.
topicVitamin-B6-Fatigue-Randomized-Trial
claimThis study investigated the efficacy of supplementation with B vitamins and magnesium in alleviating fatigue, improving disease activity, and health-related quality of life (HRQoL) in patients with inflammatory bowel disease (IBD) based on patient-reported outcomes.
evidence level4
citationRamezani E (2026)
sourceEffects of B vitamins and magnesium on fatigue, disease activity and quality of life in inflammatory bowel disease.
topicVitamin-B6-Fatigue-Randomized-Trial
claimIn this randomized, double-blind, placebo-controlled trial, 98 adults with IBD in remission were randomized (1:1) to receive daily supplementation with vitamins B 1 , B 6 , B 12 , and magnesium or a matching placebo for 4 weeks.
evidence level4
citationRamezani E (2026)
sourceEffects of B vitamins and magnesium on fatigue, disease activity and quality of life in inflammatory bowel disease.

Source documents

  1. A nutritional blend of taurine, vitamins B6, B9, and B12 improves motivated behaviors in healthy adults-a double-blinded randomized clinical trial.
  2. Effects of B vitamins and magnesium on fatigue, disease activity and quality of life in inflammatory bowel disease.