evidence table
Vitamin B12 Deficiency Evidence Table
Structured evidence table for Vitamin B12 Deficiency, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Vitamin B12 Deficiency | In Australians aged over 50 years, the prevalence of vitamin B12 deficiency ranges from 5.2 to 6.3%,,and refugees from Sudan, Bhutan, Iran, Iraq and Afghanistan are at particularly high risk (20 to 30%). | 3 | Bedz Darya (2026) | Vitamin B12 deficiency: testing and treatment |
| Vitamin B12 Deficiency | 4 Diagnosing vitamin B12 deficiency remains challenging because, despite multiple available tests, none is universally reliable or diagnostic in isolation.It is essential to consider the patient’s risk factors or symptoms in conjunction with various biochemical markers to establish a diagnosis. | 3 | Bedz Darya (2026) | Vitamin B12 deficiency: testing and treatment |
| Vitamin B12 Deficiency | The most important risk factors and the mechanism by which they cause B12 deficiency are listed in. | 3 | Bedz Darya (2026) | Vitamin B12 deficiency: testing and treatment |
| Vitamin B12 Deficiency | 1 2 3 Vitamin B12 deficiency has been recognised as a health concern for over a century. | 3 | Bedz Darya (2026) | Vitamin B12 deficiency: testing and treatment |
| Vitamin B12 Deficiency | Other key differentiators of pseudo-TMA include progressive anemia, often with irregular red cell morphology; evidence of pancytopenia, neutropenia, and reticulocytopenia; and LDH levels exceeding 2500 units/L. | 4 | Bertucci HK (2026) | Vitamin B12 Deficiency-Associated Pseudo-Thrombotic Microangiopathy in a Patient on Longstanding Oral B12 Supplementation. |
| Vitamin B12 Deficiency | In 2.5% of cases, it can manifest as pseudo-thrombotic microangiopathy (pseudo-TMA), which mimics thrombotic thrombocytopenic purpura (TTP), an emergent hemolytic microangiopathy. | 4 | Bertucci HK (2026) | Vitamin B12 Deficiency-Associated Pseudo-Thrombotic Microangiopathy in a Patient on Longstanding Oral B12 Supplementation. |
| Vitamin B12 Deficiency | This case report discusses a stable-appearing 45-year-old female with progressive fatigue, heavy menstrual bleeding, bleeding gums, and easy bruising. | 4 | Bertucci HK (2026) | Vitamin B12 Deficiency-Associated Pseudo-Thrombotic Microangiopathy in a Patient on Longstanding Oral B12 Supplementation. |
Source documents