evidence table

Vitamin B12 Deficiency Evidence Table

Structured evidence table for Vitamin B12 Deficiency, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Vitamin B12 DeficiencyIn Australians aged over 50 years, the prevalence of vitamin B12 deficiency ranges from 5.2 to 6.3%,,and refugees from Sudan, Bhutan, Iran, Iraq and Afghanistan are at particularly high risk (20 to 30%).3Bedz Darya (2026)Vitamin B12 deficiency: testing and treatment
Vitamin B12 Deficiency4 Diagnosing vitamin B12 deficiency remains challenging because, despite multiple available tests, none is universally reliable or diagnostic in isolation.It is essential to consider the patient’s risk factors or symptoms in conjunction with various biochemical markers to establish a diagnosis.3Bedz Darya (2026)Vitamin B12 deficiency: testing and treatment
Vitamin B12 DeficiencyThe most important risk factors and the mechanism by which they cause B12 deficiency are listed in.3Bedz Darya (2026)Vitamin B12 deficiency: testing and treatment
Vitamin B12 Deficiency1 2 3 Vitamin B12 deficiency has been recognised as a health concern for over a century.3Bedz Darya (2026)Vitamin B12 deficiency: testing and treatment
Vitamin B12 DeficiencyOther key differentiators of pseudo-TMA include progressive anemia, often with irregular red cell morphology; evidence of pancytopenia, neutropenia, and reticulocytopenia; and LDH levels exceeding 2500 units/L.4Bertucci HK (2026)Vitamin B12 Deficiency-Associated Pseudo-Thrombotic Microangiopathy in a Patient on Longstanding Oral B12 Supplementation.
Vitamin B12 DeficiencyIn 2.5% of cases, it can manifest as pseudo-thrombotic microangiopathy (pseudo-TMA), which mimics thrombotic thrombocytopenic purpura (TTP), an emergent hemolytic microangiopathy.4Bertucci HK (2026)Vitamin B12 Deficiency-Associated Pseudo-Thrombotic Microangiopathy in a Patient on Longstanding Oral B12 Supplementation.
Vitamin B12 DeficiencyThis case report discusses a stable-appearing 45-year-old female with progressive fatigue, heavy menstrual bleeding, bleeding gums, and easy bruising.4Bertucci HK (2026)Vitamin B12 Deficiency-Associated Pseudo-Thrombotic Microangiopathy in a Patient on Longstanding Oral B12 Supplementation.
topicVitamin B12 Deficiency
claimIn Australians aged over 50 years, the prevalence of vitamin B12 deficiency ranges from 5.2 to 6.3%,,and refugees from Sudan, Bhutan, Iran, Iraq and Afghanistan are at particularly high risk (20 to 30%).
evidence level3
citationBedz Darya (2026)
sourceVitamin B12 deficiency: testing and treatment
topicVitamin B12 Deficiency
claim4 Diagnosing vitamin B12 deficiency remains challenging because, despite multiple available tests, none is universally reliable or diagnostic in isolation.It is essential to consider the patient’s risk factors or symptoms in conjunction with various biochemical markers to establish a diagnosis.
evidence level3
citationBedz Darya (2026)
sourceVitamin B12 deficiency: testing and treatment
topicVitamin B12 Deficiency
claimThe most important risk factors and the mechanism by which they cause B12 deficiency are listed in.
evidence level3
citationBedz Darya (2026)
sourceVitamin B12 deficiency: testing and treatment
topicVitamin B12 Deficiency
claim1 2 3 Vitamin B12 deficiency has been recognised as a health concern for over a century.
evidence level3
citationBedz Darya (2026)
sourceVitamin B12 deficiency: testing and treatment
topicVitamin B12 Deficiency
claimOther key differentiators of pseudo-TMA include progressive anemia, often with irregular red cell morphology; evidence of pancytopenia, neutropenia, and reticulocytopenia; and LDH levels exceeding 2500 units/L.
evidence level4
citationBertucci HK (2026)
sourceVitamin B12 Deficiency-Associated Pseudo-Thrombotic Microangiopathy in a Patient on Longstanding Oral B12 Supplementation.
topicVitamin B12 Deficiency
claimIn 2.5% of cases, it can manifest as pseudo-thrombotic microangiopathy (pseudo-TMA), which mimics thrombotic thrombocytopenic purpura (TTP), an emergent hemolytic microangiopathy.
evidence level4
citationBertucci HK (2026)
sourceVitamin B12 Deficiency-Associated Pseudo-Thrombotic Microangiopathy in a Patient on Longstanding Oral B12 Supplementation.
topicVitamin B12 Deficiency
claimThis case report discusses a stable-appearing 45-year-old female with progressive fatigue, heavy menstrual bleeding, bleeding gums, and easy bruising.
evidence level4
citationBertucci HK (2026)
sourceVitamin B12 Deficiency-Associated Pseudo-Thrombotic Microangiopathy in a Patient on Longstanding Oral B12 Supplementation.

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Source documents

  1. Vitamin B12 deficiency: testing and treatment
  2. Vitamin B12 Deficiency-Associated Pseudo-Thrombotic Microangiopathy in a Patient on Longstanding Oral B12 Supplementation.