Structured evidence table for Vitamin B1 Cognition Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Vitamin B1 Cognition Meta-Analysis | In the United States, while mortality attributed to heart disease, stroke, and human immunodeficiency virus (HIV) declined between 2000 and 2021, deaths related to Alzheimer's disease increased by more than 140% []. | 1 | Muacevic Alexander (2026) | Determining the Effects of Lifestyle Factors Including Smoking, Alcohol Consumption, Physical Activity, and Diet on the Risk and Progression of Dementia: A Systematic Review |
| Vitamin B1 Cognition Meta-Analysis | 5 8 Existing evidence from different studies has shown that these factors may exert their effect through different mechanisms, including neurobiological pathways, by activating sensorineural networks in the prefrontal and hippocampal areas of the brain, hippocampal atrophy, reduction in brain volume, and interaction with genetic risk factor components, such as APOEe4 [-]. | 1 | Muacevic Alexander (2026) | Determining the Effects of Lifestyle Factors Including Smoking, Alcohol Consumption, Physical Activity, and Diet on the Risk and Progression of Dementia: A Systematic Review |
| Vitamin B1 Cognition Meta-Analysis | With the burden of dementia increasing, and the potential for prevention through modifiable lifestyle factors, there is therefore a need for more research into specific predisposing and progression risk factors in order to develop a comprehensive and preventive strategy []. | 1 | Muacevic Alexander (2026) | Determining the Effects of Lifestyle Factors Including Smoking, Alcohol Consumption, Physical Activity, and Diet on the Risk and Progression of Dementia: A Systematic Review |
| Vitamin B1 Cognition Meta-Analysis | 1 Dementia is a major cause of individuals becoming dependent, especially among the elderly. | 1 | Muacevic Alexander (2026) | Determining the Effects of Lifestyle Factors Including Smoking, Alcohol Consumption, Physical Activity, and Diet on the Risk and Progression of Dementia: A Systematic Review |
| Vitamin B1 Cognition Meta-Analysis | Concurrently, the number of individuals affected by dementia is anticipated to nearly triple by 2050, with associated treatment costs projected to reach US$2.8 trillion by 2030 []. | 1 | Liu Xing (2026) | Nutritional supplements and cognition in healthy aging and mild cognitive impairment patients: a systematic review and network meta-analysis |
| Vitamin B1 Cognition Meta-Analysis | In addition, omega-3 fatty acids support synaptic plasticity and exert anti-inflammatory effects; however, evidence is mixed, as randomized trials in healthy older adults show limited benefits [,], while several analyses report modest improvements in aged or MCI patients [,]. | 1 | Liu Xing (2026) | Nutritional supplements and cognition in healthy aging and mild cognitive impairment patients: a systematic review and network meta-analysis |
| Vitamin B1 Cognition Meta-Analysis | Observational studies and recent trials involving antioxidant nutrients, such as pomegranate juice and resveratrol, alongside polyphenols, suggest potential protection for specific cognitive domains (e.g., memory) and reduced dementia risk, although effects are heterogeneous and causality remains unconfirmed [,]. | 1 | Liu Xing (2026) | Nutritional supplements and cognition in healthy aging and mild cognitive impairment patients: a systematic review and network meta-analysis |
| Vitamin B1 Cognition Meta-Analysis | 1 2 3 4 5 6 7 8 9 10 The World Health Organization (WHO) projects that by 2050, the global population aged 60 and above will reach 2.1 billion, highlighting the inevitability of global aging []. | 1 | Liu Xing (2026) | Nutritional supplements and cognition in healthy aging and mild cognitive impairment patients: a systematic review and network meta-analysis |
Source documents