topicMelatonin Sleep Quality Meta-Analysis
claimMelatonin is a commonly used sleep aid, though its effects on postoperative sleep after total joint arthroplasty (TJA) remain unclear.
evidence level1
citationRazick DI (2026)
sourceEvaluating Whether Melatonin Impacts Postoperative Sleep Following Total Joint Arthroplasty: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
topicMelatonin Sleep Quality Meta-Analysis
claimTherefore, the objective of this study was to evaluate the effect of melatonin on subjective and objective sleep measures of postoperative sleep after TJA.
evidence level1
citationRazick DI (2026)
sourceEvaluating Whether Melatonin Impacts Postoperative Sleep Following Total Joint Arthroplasty: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
topicMelatonin Sleep Quality Meta-Analysis
claimWhile exogenous melatonin supplements are used to manage the condition, there is limited evidence available on the efficacy of sustained-release (SR) melatonin formulations.
evidence level2
citationThanawala S (2026)
sourceEfficacy and Safety of Sustained-Release Melatonin Capsules (2 mg) in Healthy Adults with Poor Sleep Quality: A Randomized, Double-Blind, Placebo-Controlled Trial.
topicMelatonin Sleep Quality Meta-Analysis
claimSupplementation with melatonin-SR 2 mg capsule at night for 28 days was found to be effective and safe in improving objective and subjective sleep quality outcomes and overall well-being in the trial population.
evidence level2
citationThanawala S (2026)
sourceEfficacy and Safety of Sustained-Release Melatonin Capsules (2 mg) in Healthy Adults with Poor Sleep Quality: A Randomized, Double-Blind, Placebo-Controlled Trial.
topicMelatonin Sleep Quality Meta-Analysis
claimSleep disturbances and poor sleep quality are growing public health concerns, adversely affecting both physical and mental health.
evidence level2
citationThanawala S (2026)
sourceEfficacy and Safety of Sustained-Release Melatonin Capsules (2 mg) in Healthy Adults with Poor Sleep Quality: A Randomized, Double-Blind, Placebo-Controlled Trial.