Melissa Sleep Quality Meta-analysis: What the Evidence Says

Quick Answer

Melissa Sleep Quality Meta-analysis has 2 source documents in the current Migaku evidence database. The strongest available sources in this first pass are mixed biomedical and public-health sources, so conclusions should be framed as evidence-aware guidance rather than medical advice.

Key Takeaways

• This page is generated only from sources stored in the Migaku evidence knowledge base.
• Current evidence mix: 1 preclinical study, 1 research article.
• Claims should be interpreted with the source type, study design, population, and publication date in mind.
• This article is educational and does not replace care from a qualified clinician.

Evidence Map

What The Sources Report

• Chronic sleep disturbances are increasingly recognized as significant risk factors for a range of health conditions, including cardiovascular disease, diabetes, obesity, depression, and neurodegenerative disorders such as Alzheimer's disease. [Jee Hye Jin (2026); evidence level 4]
• These findings underscore the significant public health impact of insomnia and highlight the need for therapeutic strategies with improved safety profiles and well-defined mechanisms of action. [Jee Hye Jin (2026); evidence level 4]
• Conversely, evidence suggests thatmay exert rapid central effects, independently of sleep, through modulation of neurotransmitters and stress-related neuroendocrine pathways (,,). [Rondanelli Mariangela (2026); evidence level 4]

How To Read This Evidence

Evidence level 1 generally reflects systematic reviews or meta-analyses. Level 2 includes randomized trials, guidelines, or public-health guidance. Level 3 usually reflects observational or narrative-review evidence. Level 4 is weaker or early-stage evidence. The level is a sorting aid, not a final quality grade.

Practical Interpretation

For melissa sleep quality meta-analysis, the current source set is useful for orientation, but it is not yet broad enough for strong claims. Use cautious language and keep conclusions close to the cited sources.

Limits Of This First Pass

This is a small-batch MVP article. It uses the first ingested sources for this topic and should be expanded with more targeted searches, license review, and human editorial checks before being treated as a definitive review.

References

• Jee Hye Jin (2026). Hypnotic Effects of Hypericum perforatum L. and Melissa officinalis L. Through Adenosine and Melatonin Receptors. DOI: 10.3390/nu18111666. PMCID: PMC13258432. PMID: 42280309. License: CC BY 4.0. https://pmc.ncbi.nlm.nih.gov/articles/PMC13258432/
• Rondanelli Mariangela (2026). Melissa phospholipids improves sleep quality and mental well-being: concluding results from clinical study in adults with emotional distress. DOI: 10.29219/fnr.v70.13729. PMCID: PMC12952214. PMID: 41777239. License: CC BY 4.0. https://pmc.ncbi.nlm.nih.gov/articles/PMC12952214/

Safety Note

Health information can change, and individual risk depends on medical history, medications, pregnancy status, age, and diagnosis. Talk with a qualified clinician before changing treatment, supplement, or medication routines.