Does Citrulline Muscle Recovery Meta-Analysis work?

Updated July 2026

Quick Answer

Citrulline Muscle Recovery Meta-Analysis has evidence relevant to strength of evidence and what the studies can or cannot prove, but conclusions should stay close to the cited sources. One representative finding is: For example, citrulline supplementation has been reported to improve cycling time-trial performance and oxygen uptake kinetics [,], while acute CM ingestion has also been associated with improved resistance exercise performance and reduced ratings of perceived exertion (RPE) [,].

Key Takeaways

  • 01For example, citrulline supplementation has been reported to improve cycling time-trial performance and oxygen uptake kinetics [,], while acute CM ingestion has also been associated with improved resistance exercise performance and reduced ratings of perceived exertion (RPE) [,]. [Yamanaka Ryo (2026)]
  • 02For example, creatine-based supplementation has improved repeated sprint performance in some treadmill- and field-based protocols [,], whereas interventions targeting related nitric oxide pathways do not necessarily enhance anaerobic performance in trained athletes []. [Yamanaka Ryo (2026)]
  • 03However, evidence regarding the effects of CM on true maximal sprint performance remains limited. [Yamanaka Ryo (2026)]
  • 041 2 Short-distance sprint performance is influenced by both energetic and intramuscular factors. [Yamanaka Ryo (2026)]
The current Migaku evidence database contains 1 reusable source document for Citrulline Muscle Recovery Meta-Analysis. This answer focuses on strength of evidence and what the studies can or cannot prove. - For example, citrulline supplementation has been reported to improve cycling time-trial performance and oxygen uptake kinetics [,], while acute CM ingestion has also been associated with improved resistance exercise performance and reduced ratings of perceived exertion (RPE) [,]. [Yamanaka Ryo (2026); evidence level 2] - For example, creatine-based supplementation has improved repeated sprint performance in some treadmill- and field-based protocols [,], whereas interventions targeting related nitric oxide pathways do not necessarily enhance anaerobic performance in trained athletes []. [Yamanaka Ryo (2026); evidence level 2] - However, evidence regarding the effects of CM on true maximal sprint performance remains limited. [Yamanaka Ryo (2026); evidence level 2] - 1 2 Short-distance sprint performance is influenced by both energetic and intramuscular factors. [Yamanaka Ryo (2026); evidence level 2] Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording. This page is educational. People with medical conditions, pregnancy, medication use, or unusual symptoms should ask a qualified clinician before changing supplements, medication, or treatment routines.

Sources

  1. Effects of Acute Citrulline Malate Supplementation on Repeated 100 m Sprint Performance in Trained Sprinters: A Randomized Crossover Study