Magnesium Glycinate Muscle Soreness Meta-analysis: What the Evidence Says

Quick Answer

Magnesium Glycinate Muscle Soreness Meta-analysis has 2 source documents in the current Migaku evidence database. The strongest available sources in this first pass are systematic review, so conclusions should be framed as evidence-aware guidance rather than medical advice.

Key Takeaways

• This page is generated only from sources stored in the Migaku evidence knowledge base.
• Current evidence mix: 1 systematic review, 1 observational study.
• Claims should be interpreted with the source type, study design, population, and publication date in mind.
• This article is educational and does not replace care from a qualified clinician.

Evidence Map

What The Sources Report

• Approximately 50% of Mg is stored in bones and the remaining 50% inside cells and organs, while less than 1% is found in the bloodstream. [Tarsitano Maria Grazia (2024); evidence level 1]
• A reduction in Mg concentration (hypomagnesemia) can be observed especially after intense and prolonged exercise whereas brief yet intense bouts of exercise may lead to an increased Mg concentration (hypermagnesemia). [Tarsitano Maria Grazia (2024); evidence level 1]
• In a cross-sectional study also form Saudi Arabia, magnesium was one of the supplements found to be consumed by almost 30% of the participants. [Abutaima Rana (2025); evidence level 3]
• Costello et al., 2021 The risk of several chronic conditions, including metabolic syndrome and cardiovascular disease, as well as certain cancers (esophageal, prostate, and colon) and overall mortality, has been linked to low magnesium intakes combined with high calcium intakes and high calcium-to-magnesium intake ratios. [Abutaima Rana (2025); evidence level 3]

How To Read This Evidence

Evidence level 1 generally reflects systematic reviews or meta-analyses. Level 2 includes randomized trials, guidelines, or public-health guidance. Level 3 usually reflects observational or narrative-review evidence. Level 4 is weaker or early-stage evidence. The level is a sorting aid, not a final quality grade.

Practical Interpretation

There is at least one systematic-review style source in the current set, so it deserves more weight than single-study evidence. For magnesium glycinate muscle soreness meta-analysis, the next editorial step is to add more targeted sources and separate strong findings from early or indirect evidence.

Limits Of This First Pass

This is a small-batch MVP article. It uses the first ingested sources for this topic and should be expanded with more targeted searches, license review, and human editorial checks before being treated as a definitive review.

References

• Tarsitano Maria Grazia (2024). Effects of magnesium supplementation on muscle soreness in different type of physical activities: a systematic review. DOI: 10.1186/s12967-024-05434-x. PMCID: PMC11227245. PMID: 38970118. License: CC BY 4.0. https://pmc.ncbi.nlm.nih.gov/articles/PMC11227245/
• Abutaima Rana (2025). A multinational cross-sectional study on knowledge, attitudes, and practices towards magnesium supplements. DOI: 10.3389/fphar.2025.1550695. PMCID: PMC12066956. PMID: 40356953. License: CC BY 4.0. https://pmc.ncbi.nlm.nih.gov/articles/PMC12066956/

Safety Note

Health information can change, and individual risk depends on medical history, medications, pregnancy status, age, and diagnosis. Talk with a qualified clinician before changing treatment, supplement, or medication routines.