Citrulline Endurance Performance Meta-analysis: What the Evidence Says

Quick Answer

Citrulline Endurance Performance Meta-analysis has 2 source documents in the current Migaku evidence database. The strongest available sources in this first pass are mixed biomedical and public-health sources, so conclusions should be framed as evidence-aware guidance rather than medical advice.

Key Takeaways

• This page is generated only from sources stored in the Migaku evidence knowledge base.
• Current evidence mix: 1 research article, 1 preclinical study.
• Claims should be interpreted with the source type, study design, population, and publication date in mind.
• This article is educational and does not replace care from a qualified clinician.

Evidence Map

What The Sources Report

• Through its involvement in NO-related pathways, L-ARG supplementation has been associated with changes in vascular function and blood flow, which may influence exercise-related physiological responses (,-). [Uçar Halil (2026); evidence level 4]
• However, the findings across these studies remain inconsistent, and conclusive evidence supporting clear performance or recovery benefits has yet to be established. [Uçar Halil (2026); evidence level 4]
• Energy drink consumption has grown exponentially across adolescents, young adults, athletes, and shift workers, driven by demands for prolonged alertness and improved performance . [Muacevic Alexander (2026); evidence level 4]
• Because of heterogeneity in study designs, populations, dosing regimens, and outcome measures, no formal risk-of-bias tool or quantitative meta-analysis was applied. [Muacevic Alexander (2026); evidence level 4]

How To Read This Evidence

Evidence level 1 generally reflects systematic reviews or meta-analyses. Level 2 includes randomized trials, guidelines, or public-health guidance. Level 3 usually reflects observational or narrative-review evidence. Level 4 is weaker or early-stage evidence. The level is a sorting aid, not a final quality grade.

Practical Interpretation

For citrulline endurance performance meta-analysis, the current source set is useful for orientation, but it is not yet broad enough for strong claims. Use cautious language and keep conclusions close to the cited sources.

Limits Of This First Pass

This is a small-batch MVP article. It uses the first ingested sources for this topic and should be expanded with more targeted searches, license review, and human editorial checks before being treated as a definitive review.

References

• Uçar Halil (2026). Acute effects of citrulline malate and L-arginine, alone and in combination, on anaerobic performance indicators in highly trained taekwondo athletes. DOI: 10.3389/fnut.2026.1788549. PMCID: PMC13057471. PMID: 41958907. License: CC BY 4.0. https://pmc.ncbi.nlm.nih.gov/articles/PMC13057471/
• Muacevic Alexander (2026). Synergistic Actions of Natural Compounds for Enhancing Cognitive and Physical Performance: A Narrative Review. DOI: 10.7759/cureus.102674. PMCID: PMC12950988. PMID: 41777984. License: CC BY 4.0. https://pmc.ncbi.nlm.nih.gov/articles/PMC12950988/

Safety Note

Health information can change, and individual risk depends on medical history, medications, pregnancy status, age, and diagnosis. Talk with a qualified clinician before changing treatment, supplement, or medication routines.