evidence table

Vitamin K2 Bone Health Randomized Trial Evidence Table

Structured evidence table for Vitamin K2 Bone Health Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Vitamin K2 Bone Health Randomized TrialVitamin D deficiency has been consistently associated with adverse outcomes, including increased susceptibility to cancers, diabetes, hypertension, and cardiovascular disease [,].3D’Elia Saverio (2025)Modulation of Cardiometabolic Risk by Vitamin D and K2: Simple Supplementation or Real Drug? Uncovering the Pharmacological Properties
Vitamin K2 Bone Health Randomized TrialEpidemiological studies further indicate that populations in regions with higher sun exposure exhibit lower prevalence of deficiency and reduced mortality from chronic disease [,].3D’Elia Saverio (2025)Modulation of Cardiometabolic Risk by Vitamin D and K2: Simple Supplementation or Real Drug? Uncovering the Pharmacological Properties
Vitamin K2 Bone Health Randomized TrialThese findings are reinforced by recent large-scale analyses: for example, a 2023 study in Clinical Nutrition involving nearly 410,000 UK Biobank participants reported that individuals with severe deficiency (<30 nmol/L) had a 10% increased risk of atherosclerotic cardiovascular disease and up to 35% higher risk of cardiovascular mortality [].3D&#8217;Elia Saverio (2025)Modulation of Cardiometabolic Risk by Vitamin D and K2: Simple Supplementation or Real Drug? Uncovering the Pharmacological Properties
Vitamin K2 Bone Health Randomized Trial1 2 3 4 5 6 7 6 Vitamin D, a pleiotropic secosteroid, exerts physiological effects far beyond its classical roles in calcium homeostasis and skeletal health [].3D&#8217;Elia Saverio (2025)Modulation of Cardiometabolic Risk by Vitamin D and K2: Simple Supplementation or Real Drug? Uncovering the Pharmacological Properties
Vitamin K2 Bone Health Randomized TrialMicronutrient deficiencies are a major public health concern in low- and middle-income countries, where conventional supplementation and fortification programs are often limited by low bioavailability, fragile supply chains, cultural resistance, and poor long-term adherence.4Cho S (2026)Applying traditional K-foods to official development assistance programs for micronutrient deficiency nutrition support.
Vitamin K2 Bone Health Randomized TrialThis research note proposes a food-based alternative model that leverages selected traditional Korean foods (K-foods)- gim (dried seaweed), kimchi (fermented vegetables), and cheonggukjang (fermented soybean paste)-as culturally adaptable and nutritionally dense components of official development assistance nutrition strategies.4Cho S (2026)Applying traditional K-foods to official development assistance programs for micronutrient deficiency nutrition support.
topicVitamin K2 Bone Health Randomized Trial
claimVitamin D deficiency has been consistently associated with adverse outcomes, including increased susceptibility to cancers, diabetes, hypertension, and cardiovascular disease [,].
evidence level3
citationD&#8217;Elia Saverio (2025)
sourceModulation of Cardiometabolic Risk by Vitamin D and K2: Simple Supplementation or Real Drug? Uncovering the Pharmacological Properties
topicVitamin K2 Bone Health Randomized Trial
claimEpidemiological studies further indicate that populations in regions with higher sun exposure exhibit lower prevalence of deficiency and reduced mortality from chronic disease [,].
evidence level3
citationD&#8217;Elia Saverio (2025)
sourceModulation of Cardiometabolic Risk by Vitamin D and K2: Simple Supplementation or Real Drug? Uncovering the Pharmacological Properties
topicVitamin K2 Bone Health Randomized Trial
claimThese findings are reinforced by recent large-scale analyses: for example, a 2023 study in Clinical Nutrition involving nearly 410,000 UK Biobank participants reported that individuals with severe deficiency (<30 nmol/L) had a 10% increased risk of atherosclerotic cardiovascular disease and up to 35% higher risk of cardiovascular mortality [].
evidence level3
citationD&#8217;Elia Saverio (2025)
sourceModulation of Cardiometabolic Risk by Vitamin D and K2: Simple Supplementation or Real Drug? Uncovering the Pharmacological Properties
topicVitamin K2 Bone Health Randomized Trial
claim1 2 3 4 5 6 7 6 Vitamin D, a pleiotropic secosteroid, exerts physiological effects far beyond its classical roles in calcium homeostasis and skeletal health [].
evidence level3
citationD&#8217;Elia Saverio (2025)
sourceModulation of Cardiometabolic Risk by Vitamin D and K2: Simple Supplementation or Real Drug? Uncovering the Pharmacological Properties
topicVitamin K2 Bone Health Randomized Trial
claimMicronutrient deficiencies are a major public health concern in low- and middle-income countries, where conventional supplementation and fortification programs are often limited by low bioavailability, fragile supply chains, cultural resistance, and poor long-term adherence.
evidence level4
citationCho S (2026)
sourceApplying traditional K-foods to official development assistance programs for micronutrient deficiency nutrition support.
topicVitamin K2 Bone Health Randomized Trial
claimThis research note proposes a food-based alternative model that leverages selected traditional Korean foods (K-foods)- gim (dried seaweed), kimchi (fermented vegetables), and cheonggukjang (fermented soybean paste)-as culturally adaptable and nutritionally dense components of official development assistance nutrition strategies.
evidence level4
citationCho S (2026)
sourceApplying traditional K-foods to official development assistance programs for micronutrient deficiency nutrition support.

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Source documents

  1. Modulation of Cardiometabolic Risk by Vitamin D and K2: Simple Supplementation or Real Drug? Uncovering the Pharmacological Properties
  2. Applying traditional K-foods to official development assistance programs for micronutrient deficiency nutrition support.