evidence table
Vitamin E Skin Photoaging Randomized Trial Evidence Table
Structured evidence table for Vitamin E Skin Photoaging Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Vitamin E Skin Photoaging Randomized Trial | Accumulation of damage leads to increased reactive oxygen species and changes the properties and quantity of matrix proteins []. | 2 | Afzal Laila (2026) | Prospective, Randomized, Double‐Blind, Placebo‐Controlled Study of an Oral Antioxidant‐Rich Synbiotic Supplement on Skin Health and Photoaging |
| Vitamin E Skin Photoaging Randomized Trial | Reduced collagen has been shown to contribute to skin aging and is what contributes to wrinkle formation []. | 2 | Afzal Laila (2026) | Prospective, Randomized, Double‐Blind, Placebo‐Controlled Study of an Oral Antioxidant‐Rich Synbiotic Supplement on Skin Health and Photoaging |
| Vitamin E Skin Photoaging Randomized Trial | Astaxanthin (ASX) is an α‐hydroxy‐ketocarotenoid found in numerous bacterial species, microalgae, and marine animals, including shrimp, crab, and salmon [,]. | 2 | Afzal Laila (2026) | Prospective, Randomized, Double‐Blind, Placebo‐Controlled Study of an Oral Antioxidant‐Rich Synbiotic Supplement on Skin Health and Photoaging |
| Vitamin E Skin Photoaging Randomized Trial | 1 1 2 3 4 4 3 4 Human skin is a complex organ that covers the entire human body. | 2 | Afzal Laila (2026) | Prospective, Randomized, Double‐Blind, Placebo‐Controlled Study of an Oral Antioxidant‐Rich Synbiotic Supplement on Skin Health and Photoaging |
| Vitamin E Skin Photoaging Randomized Trial | Results At Week 12, the Microneedle + Antioxidant side demonstrated significantly greater improvements in modified Griffith's scale scores (23.9% vs 6.8%, p Conclusion Combining topical antioxidant serum with microneedling provides superior outcomes for facial rejuvenation than microneedling alone. | 2 | Liu C (2026) | A Double-Blinded, Split-Face Clinical Trial Evaluating the Effects of a Vitamin C, E, and Ferulic Acid Serum Combined with Microneedling on Facial Photoaging. |
| Vitamin E Skin Photoaging Randomized Trial | Purpose Microneedling achieves skin rejuvenation through controlled microinjury, while topical antioxidants may enhance its outcomes by neutralizing reactive oxygen species and promoting tissue repair. | 2 | Liu C (2026) | A Double-Blinded, Split-Face Clinical Trial Evaluating the Effects of a Vitamin C, E, and Ferulic Acid Serum Combined with Microneedling on Facial Photoaging. |
| Vitamin E Skin Photoaging Randomized Trial | This study evaluated whether a topical antioxidant formulation containing vitamins C, E, and ferric acid enhances facial rejuvenation outcomes when combined with microneedling. | 2 | Liu C (2026) | A Double-Blinded, Split-Face Clinical Trial Evaluating the Effects of a Vitamin C, E, and Ferulic Acid Serum Combined with Microneedling on Facial Photoaging. |
Source documents
- Prospective, Randomized, Double‐Blind, Placebo‐Controlled Study of an Oral Antioxidant‐Rich Synbiotic Supplement on Skin Health and Photoaging
- A Double-Blinded, Split-Face Clinical Trial Evaluating the Effects of a Vitamin C, E, and Ferulic Acid Serum Combined with Microneedling on Facial Photoaging.