evidence table

Vitamin E Skin Photoaging Randomized Trial Evidence Table

Structured evidence table for Vitamin E Skin Photoaging Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Vitamin E Skin Photoaging Randomized TrialAccumulation of damage leads to increased reactive oxygen species and changes the properties and quantity of matrix proteins [].2Afzal Laila (2026)Prospective, Randomized, Double‐Blind, Placebo‐Controlled Study of an Oral Antioxidant‐Rich Synbiotic Supplement on Skin Health and Photoaging
Vitamin E Skin Photoaging Randomized TrialReduced collagen has been shown to contribute to skin aging and is what contributes to wrinkle formation [].2Afzal Laila (2026)Prospective, Randomized, Double‐Blind, Placebo‐Controlled Study of an Oral Antioxidant‐Rich Synbiotic Supplement on Skin Health and Photoaging
Vitamin E Skin Photoaging Randomized TrialAstaxanthin (ASX) is an α‐hydroxy‐ketocarotenoid found in numerous bacterial species, microalgae, and marine animals, including shrimp, crab, and salmon [,].2Afzal Laila (2026)Prospective, Randomized, Double‐Blind, Placebo‐Controlled Study of an Oral Antioxidant‐Rich Synbiotic Supplement on Skin Health and Photoaging
Vitamin E Skin Photoaging Randomized Trial1 1 2 3 4 4 3 4 Human skin is a complex organ that covers the entire human body.2Afzal Laila (2026)Prospective, Randomized, Double‐Blind, Placebo‐Controlled Study of an Oral Antioxidant‐Rich Synbiotic Supplement on Skin Health and Photoaging
Vitamin E Skin Photoaging Randomized TrialResults At Week 12, the Microneedle + Antioxidant side demonstrated significantly greater improvements in modified Griffith's scale scores (23.9% vs 6.8%, p Conclusion Combining topical antioxidant serum with microneedling provides superior outcomes for facial rejuvenation than microneedling alone.2Liu C (2026)A Double-Blinded, Split-Face Clinical Trial Evaluating the Effects of a Vitamin C, E, and Ferulic Acid Serum Combined with Microneedling on Facial Photoaging.
Vitamin E Skin Photoaging Randomized TrialPurpose Microneedling achieves skin rejuvenation through controlled microinjury, while topical antioxidants may enhance its outcomes by neutralizing reactive oxygen species and promoting tissue repair.2Liu C (2026)A Double-Blinded, Split-Face Clinical Trial Evaluating the Effects of a Vitamin C, E, and Ferulic Acid Serum Combined with Microneedling on Facial Photoaging.
Vitamin E Skin Photoaging Randomized TrialThis study evaluated whether a topical antioxidant formulation containing vitamins C, E, and ferric acid enhances facial rejuvenation outcomes when combined with microneedling.2Liu C (2026)A Double-Blinded, Split-Face Clinical Trial Evaluating the Effects of a Vitamin C, E, and Ferulic Acid Serum Combined with Microneedling on Facial Photoaging.
topicVitamin E Skin Photoaging Randomized Trial
claimAccumulation of damage leads to increased reactive oxygen species and changes the properties and quantity of matrix proteins [].
evidence level2
citationAfzal Laila (2026)
sourceProspective, Randomized, Double‐Blind, Placebo‐Controlled Study of an Oral Antioxidant‐Rich Synbiotic Supplement on Skin Health and Photoaging
topicVitamin E Skin Photoaging Randomized Trial
claimReduced collagen has been shown to contribute to skin aging and is what contributes to wrinkle formation [].
evidence level2
citationAfzal Laila (2026)
sourceProspective, Randomized, Double‐Blind, Placebo‐Controlled Study of an Oral Antioxidant‐Rich Synbiotic Supplement on Skin Health and Photoaging
topicVitamin E Skin Photoaging Randomized Trial
claimAstaxanthin (ASX) is an α‐hydroxy‐ketocarotenoid found in numerous bacterial species, microalgae, and marine animals, including shrimp, crab, and salmon [,].
evidence level2
citationAfzal Laila (2026)
sourceProspective, Randomized, Double‐Blind, Placebo‐Controlled Study of an Oral Antioxidant‐Rich Synbiotic Supplement on Skin Health and Photoaging
topicVitamin E Skin Photoaging Randomized Trial
claim1 1 2 3 4 4 3 4 Human skin is a complex organ that covers the entire human body.
evidence level2
citationAfzal Laila (2026)
sourceProspective, Randomized, Double‐Blind, Placebo‐Controlled Study of an Oral Antioxidant‐Rich Synbiotic Supplement on Skin Health and Photoaging
topicVitamin E Skin Photoaging Randomized Trial
claimResults At Week 12, the Microneedle + Antioxidant side demonstrated significantly greater improvements in modified Griffith's scale scores (23.9% vs 6.8%, p Conclusion Combining topical antioxidant serum with microneedling provides superior outcomes for facial rejuvenation than microneedling alone.
evidence level2
citationLiu C (2026)
sourceA Double-Blinded, Split-Face Clinical Trial Evaluating the Effects of a Vitamin C, E, and Ferulic Acid Serum Combined with Microneedling on Facial Photoaging.
topicVitamin E Skin Photoaging Randomized Trial
claimPurpose Microneedling achieves skin rejuvenation through controlled microinjury, while topical antioxidants may enhance its outcomes by neutralizing reactive oxygen species and promoting tissue repair.
evidence level2
citationLiu C (2026)
sourceA Double-Blinded, Split-Face Clinical Trial Evaluating the Effects of a Vitamin C, E, and Ferulic Acid Serum Combined with Microneedling on Facial Photoaging.
topicVitamin E Skin Photoaging Randomized Trial
claimThis study evaluated whether a topical antioxidant formulation containing vitamins C, E, and ferric acid enhances facial rejuvenation outcomes when combined with microneedling.
evidence level2
citationLiu C (2026)
sourceA Double-Blinded, Split-Face Clinical Trial Evaluating the Effects of a Vitamin C, E, and Ferulic Acid Serum Combined with Microneedling on Facial Photoaging.

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Source documents

  1. Prospective, Randomized, Double‐Blind, Placebo‐Controlled Study of an Oral Antioxidant‐Rich Synbiotic Supplement on Skin Health and Photoaging
  2. A Double-Blinded, Split-Face Clinical Trial Evaluating the Effects of a Vitamin C, E, and Ferulic Acid Serum Combined with Microneedling on Facial Photoaging.