Structured evidence table for Vitamin C Skin Hydration Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Vitamin C Skin Hydration Meta-Analysis | 1 The phenomenon of aging is inescapable and is characterized by multiple clinical manifestations, including wrinkles, reduced skin density, loss of elasticity, xerosis, uneven pigmentation, telangiectasia, sagging, and impaired wound healing. | 1 | Nukaly Houriah Y. (2026) | Oral and topical peptides for skin aging: systematic review and meta-analysis of randomized controlled trials |
| Vitamin C Skin Hydration Meta-Analysis | Peptides act as signaling molecules that mimic the body's natural processes to stimulate collagen synthesis, as well as enhancing other extracellular matrix (ECM) components such as hyaluronic acid by fibroblasts, help to rebuild the skin's structural integrity, resulting in improved skin texture, reduced wrinkles, and increased elasticity and hydration. | 1 | Nukaly Houriah Y. (2026) | Oral and topical peptides for skin aging: systematic review and meta-analysis of randomized controlled trials |
| Vitamin C Skin Hydration Meta-Analysis | 2 4 A prime example of the efficacy of oral supplements is hydrolyzed collagen peptides, that significantly improved skin hydration, elasticity, roughness, and density in a randomized, placebo-controlled trial (). | 1 | Nukaly Houriah Y. (2026) | Oral and topical peptides for skin aging: systematic review and meta-analysis of randomized controlled trials |
| Vitamin C Skin Hydration Meta-Analysis | p p Oral polypeptides significantly improve skin hydration (Mean Difference [MD]: 5.80,< 0.01) and wrinkle reduction (MD: 0.35,= 0.05), outperforming topical formulations. | 1 | Nukaly Houriah Y. (2026) | Oral and topical peptides for skin aging: systematic review and meta-analysis of randomized controlled trials |
| Vitamin C Skin Hydration Meta-Analysis | As for clinical studies, the intervention increased skin hydration (MD = 2.12, 95% CI [1.02; 3.21]) while decreased TEWL (MD = -0.68, 95% CI [-1.21; -0.16]). | 1 | Liang Y (2026) | Impact of Antioxidant-Rich Whole Foods or Supplements on Skin Health: A Systematic Review and Meta-Analysis of Preclinical and Clinical Studies. |
| Vitamin C Skin Hydration Meta-Analysis | Conclusions Antioxidant-rich whole foods or supplements intake improved overall skin health and skin disorder conditions. | 1 | Liang Y (2026) | Impact of Antioxidant-Rich Whole Foods or Supplements on Skin Health: A Systematic Review and Meta-Analysis of Preclinical and Clinical Studies. |
| Vitamin C Skin Hydration Meta-Analysis | Background Antioxidant supplements have been reported to confer benefits for skin health; however, these effects remain inconclusive and lack systematic evaluation. | 1 | Liang Y (2026) | Impact of Antioxidant-Rich Whole Foods or Supplements on Skin Health: A Systematic Review and Meta-Analysis of Preclinical and Clinical Studies. |
| Vitamin C Skin Hydration Meta-Analysis | Methods This systematic review and meta-analysis assessed the impact of antioxidant-rich whole foods or supplements on various skin health outcomes by compiling data from five databases, including 94 eligible preclinical and clinical studies. | 1 | Liang Y (2026) | Impact of Antioxidant-Rich Whole Foods or Supplements on Skin Health: A Systematic Review and Meta-Analysis of Preclinical and Clinical Studies. |
Source documents