topicVitamin C Skin Health Randomized Trial
claimp p 1 The THD‐AA serum reduced ROS formation by 88% after 30 min, 87% after 60 min, and 82% after 120 min.
evidence level4
citationMaloney McKenzie E. (2026)
sourceHydroquinone‐Free, Tetrahexyldecyl Ascorbate Antioxidant Serum for Hyperpigmented and Photodamaged Skin to Achieve Skin Health
topicVitamin C Skin Health Randomized Trial
claimAt week 12 the following statistics were found in the THD‐AA serum group: The results from the subjective self‐assessment conducted at week 12 were as follows: There were no significant changes from baseline for any tolerability parameter (burning, itching, or stinging).
evidence level4
citationMaloney McKenzie E. (2026)
sourceHydroquinone‐Free, Tetrahexyldecyl Ascorbate Antioxidant Serum for Hyperpigmented and Photodamaged Skin to Achieve Skin Health
topicVitamin C Skin Health Randomized Trial
claimThis represents a 22%–42% enhancement in antioxidant activity compared to other derivatives, likely a result of its superior skin penetration [,,].
evidence level4
citationMaloney McKenzie E. (2026)
sourceHydroquinone‐Free, Tetrahexyldecyl Ascorbate Antioxidant Serum for Hyperpigmented and Photodamaged Skin to Achieve Skin Health
topicVitamin C Skin Health Randomized Trial
claimAA DEJ FDA HEV OTC ROS THD THD‐AA Serum 1 2 3 2 4 5 Photodamage accelerates the natural skin aging process, upregulating collagen degradation, downregulating collagen synthesis, and accelerating the production of free radicals.
evidence level4
citationMaloney McKenzie E. (2026)
sourceHydroquinone‐Free, Tetrahexyldecyl Ascorbate Antioxidant Serum for Hyperpigmented and Photodamaged Skin to Achieve Skin Health