evidence table
Vitamin C Skin Collagen Randomized Trial Evidence Table
Structured evidence table for Vitamin C Skin Collagen Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Vitamin C Skin Collagen Randomized Trial | Photoaging may not only affect quality of life, but also create substantial financial burden for patients, making its prevention and the practice of evidence-based treatments essential. | 3 | Tsai Jerry (2026) | Photoaging: Update on Pathogenesis, Prevention, and Treatment |
| Vitamin C Skin Collagen Randomized Trial | UVB, which primarily affects the epidermis and superficial dermis, is classically associated with the development of skin cancer through creation of cyclobutene pyrimidine dimers, pyrimidine-pyrimidone (6-4) photoproducts, and reactive oxygen species (ROS), as well as suppression of immune surveillance against tumors. | 3 | Tsai Jerry (2026) | Photoaging: Update on Pathogenesis, Prevention, and Treatment |
| Vitamin C Skin Collagen Randomized Trial | ECM degradation from chronic sun exposure also results in increased skin fragility and susceptibility of cutaneous vasculature to minor trauma, clinically manifesting as purpuric lesions known as solar purpura. | 3 | Tsai Jerry (2026) | Photoaging: Update on Pathogenesis, Prevention, and Treatment |
| Vitamin C Skin Collagen Randomized Trial | 1 2 Skin aging occurs through the passage of time (intrinsic aging) accompanied by environmental damage (extrinsic aging). | 3 | Tsai Jerry (2026) | Photoaging: Update on Pathogenesis, Prevention, and Treatment |
| Vitamin C Skin Collagen Randomized Trial | Collagen, along with antioxidants such as curcumin and glutathione, have gained increased utilization/awareness in recent years, providing dermal health benefits especially in women who experience declining or loss of estrogen with aging. | 4 | Arbex Priscila (2026) | Collagen, Curcumin, and Glutathione to Enhance Dermal Health in Aging Women with Declining Estrogen Levels —A Narrative Review |
| Vitamin C Skin Collagen Randomized Trial | The evidence of oral collagen as a nutraceutical is robust for improving several aspects of dermal health. | 4 | Arbex Priscila (2026) | Collagen, Curcumin, and Glutathione to Enhance Dermal Health in Aging Women with Declining Estrogen Levels —A Narrative Review |
| Vitamin C Skin Collagen Randomized Trial | For example, the epidermis is without a blood supply and does not have the same circulation and nutrient delivery found in the dermis [–]. | 4 | Arbex Priscila (2026) | Collagen, Curcumin, and Glutathione to Enhance Dermal Health in Aging Women with Declining Estrogen Levels —A Narrative Review |
| Vitamin C Skin Collagen Randomized Trial | The present narrative review is an extension of a larger project that covered polyphenols and phytoestrogens. | 4 | Arbex Priscila (2026) | Collagen, Curcumin, and Glutathione to Enhance Dermal Health in Aging Women with Declining Estrogen Levels —A Narrative Review |
Source documents