topicVitamin C Skin Collagen Meta-Analysis
claimIntroduction Skin aging manifests as wrinkles, reduced elasticity, and roughness due to intrinsic and extrinsic factors.
evidence level1
citationNukaly HY (2026)
sourceOral and topical peptides for skin aging: systematic review and meta-analysis of randomized controlled trials.
topicVitamin C Skin Collagen Meta-Analysis
claimPeptides, particularly oral formulations, significantly improved hydration and brightness, with a modest pooled effect on wrinkle reduction (MD = 0.27, p = 0.04).
evidence level1
citationNukaly HY (2026)
sourceOral and topical peptides for skin aging: systematic review and meta-analysis of randomized controlled trials.
topicVitamin C Skin Collagen Meta-Analysis
claimPeptide-based therapies enhance collagen synthesis and extracellular matrix integrity.
evidence level1
citationNukaly HY (2026)
sourceOral and topical peptides for skin aging: systematic review and meta-analysis of randomized controlled trials.
topicVitamin C Skin Collagen Meta-Analysis
claimAs for clinical studies, the intervention increased skin hydration (MD = 2.12, 95% CI [1.02; 3.21]) while decreased TEWL (MD = -0.68, 95% CI [-1.21; -0.16]).
evidence level1
citationLiang Y (2026)
sourceImpact of Antioxidant-Rich Whole Foods or Supplements on Skin Health: A Systematic Review and Meta-Analysis of Preclinical and Clinical Studies.
topicVitamin C Skin Collagen Meta-Analysis
claimConclusions Antioxidant-rich whole foods or supplements intake improved overall skin health and skin disorder conditions.
evidence level1
citationLiang Y (2026)
sourceImpact of Antioxidant-Rich Whole Foods or Supplements on Skin Health: A Systematic Review and Meta-Analysis of Preclinical and Clinical Studies.
topicVitamin C Skin Collagen Meta-Analysis
claimBackground Antioxidant supplements have been reported to confer benefits for skin health; however, these effects remain inconclusive and lack systematic evaluation.
evidence level1
citationLiang Y (2026)
sourceImpact of Antioxidant-Rich Whole Foods or Supplements on Skin Health: A Systematic Review and Meta-Analysis of Preclinical and Clinical Studies.
topicVitamin C Skin Collagen Meta-Analysis
claimMethods This systematic review and meta-analysis assessed the impact of antioxidant-rich whole foods or supplements on various skin health outcomes by compiling data from five databases, including 94 eligible preclinical and clinical studies.
evidence level1
citationLiang Y (2026)
sourceImpact of Antioxidant-Rich Whole Foods or Supplements on Skin Health: A Systematic Review and Meta-Analysis of Preclinical and Clinical Studies.