Vitamin C Skin Collagen Meta-Analysis Evidence Table

Structured evidence table for Vitamin C Skin Collagen Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Vitamin C Skin Collagen Meta-AnalysisIntroduction Skin aging manifests as wrinkles, reduced elasticity, and roughness due to intrinsic and extrinsic factors.1Nukaly HY (2026)Oral and topical peptides for skin aging: systematic review and meta-analysis of randomized controlled trials.
Vitamin C Skin Collagen Meta-AnalysisPeptides, particularly oral formulations, significantly improved hydration and brightness, with a modest pooled effect on wrinkle reduction (MD = 0.27, p = 0.04).1Nukaly HY (2026)Oral and topical peptides for skin aging: systematic review and meta-analysis of randomized controlled trials.
Vitamin C Skin Collagen Meta-AnalysisPeptide-based therapies enhance collagen synthesis and extracellular matrix integrity.1Nukaly HY (2026)Oral and topical peptides for skin aging: systematic review and meta-analysis of randomized controlled trials.
Vitamin C Skin Collagen Meta-AnalysisAs for clinical studies, the intervention increased skin hydration (MD = 2.12, 95% CI [1.02; 3.21]) while decreased TEWL (MD = -0.68, 95% CI [-1.21; -0.16]).1Liang Y (2026)Impact of Antioxidant-Rich Whole Foods or Supplements on Skin Health: A Systematic Review and Meta-Analysis of Preclinical and Clinical Studies.
Vitamin C Skin Collagen Meta-AnalysisConclusions Antioxidant-rich whole foods or supplements intake improved overall skin health and skin disorder conditions.1Liang Y (2026)Impact of Antioxidant-Rich Whole Foods or Supplements on Skin Health: A Systematic Review and Meta-Analysis of Preclinical and Clinical Studies.
Vitamin C Skin Collagen Meta-AnalysisBackground Antioxidant supplements have been reported to confer benefits for skin health; however, these effects remain inconclusive and lack systematic evaluation.1Liang Y (2026)Impact of Antioxidant-Rich Whole Foods or Supplements on Skin Health: A Systematic Review and Meta-Analysis of Preclinical and Clinical Studies.
Vitamin C Skin Collagen Meta-AnalysisMethods This systematic review and meta-analysis assessed the impact of antioxidant-rich whole foods or supplements on various skin health outcomes by compiling data from five databases, including 94 eligible preclinical and clinical studies.1Liang Y (2026)Impact of Antioxidant-Rich Whole Foods or Supplements on Skin Health: A Systematic Review and Meta-Analysis of Preclinical and Clinical Studies.

Source documents

  1. Oral and topical peptides for skin aging: systematic review and meta-analysis of randomized controlled trials.
  2. Impact of Antioxidant-Rich Whole Foods or Supplements on Skin Health: A Systematic Review and Meta-Analysis of Preclinical and Clinical Studies.