Structured evidence table for Vitamin C Collagen Skin Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Vitamin C Collagen Skin Meta-Analysis | Introduction Skin aging manifests as wrinkles, reduced elasticity, and roughness due to intrinsic and extrinsic factors. | 1 | Nukaly HY (2026) | Oral and topical peptides for skin aging: systematic review and meta-analysis of randomized controlled trials. |
| Vitamin C Collagen Skin Meta-Analysis | Peptides, particularly oral formulations, significantly improved hydration and brightness, with a modest pooled effect on wrinkle reduction (MD = 0.27, p = 0.04). | 1 | Nukaly HY (2026) | Oral and topical peptides for skin aging: systematic review and meta-analysis of randomized controlled trials. |
| Vitamin C Collagen Skin Meta-Analysis | Peptide-based therapies enhance collagen synthesis and extracellular matrix integrity. | 1 | Nukaly HY (2026) | Oral and topical peptides for skin aging: systematic review and meta-analysis of randomized controlled trials. |
| Vitamin C Collagen Skin Meta-Analysis | However, these treatments are associated with adverse effects, particularly with prolonged use [,,,]. | 1 | Liang Yuxin (2026) | Impact of Antioxidant-Rich Whole Foods or Supplements on Skin Health: A Systematic Review and Meta-Analysis of Preclinical and Clinical Studies |
| Vitamin C Collagen Skin Meta-Analysis | These properties may further improve skin barrier function, support collagen synthesis, increase hydration, and alleviate inflammation-associated skin conditions [,,,,,,,]. | 1 | Liang Yuxin (2026) | Impact of Antioxidant-Rich Whole Foods or Supplements on Skin Health: A Systematic Review and Meta-Analysis of Preclinical and Clinical Studies |
| Vitamin C Collagen Skin Meta-Analysis | Most studies focus on isolated antioxidant supplements, leaving a gap in evidence regarding antioxidant-rich whole food interventions and comparative outcomes across various skin conditions. | 1 | Liang Yuxin (2026) | Impact of Antioxidant-Rich Whole Foods or Supplements on Skin Health: A Systematic Review and Meta-Analysis of Preclinical and Clinical Studies |
| Vitamin C Collagen Skin Meta-Analysis | 1 2 As the most extensive organ of the human body, the skin functions as a vital interface against environmental insults, regulating temperature, preventing dehydration, and playing a crucial role in immune defense []. | 1 | Liang Yuxin (2026) | Impact of Antioxidant-Rich Whole Foods or Supplements on Skin Health: A Systematic Review and Meta-Analysis of Preclinical and Clinical Studies |
Source documents