topicPolypodium Leucotomos Skin Photoprotection Randomized Trial
claimResults : Throughout the intervention, MED gradually increased, while Δ a* decreased in the IP group.
evidence level2
citationKeršmanc P (2025)
sourceEffects of Eight-Week Supplementation Containing Red Orange and <i>Polypodium leucotomos</i> Extracts on UVB-Induced Skin Responses: A Randomized Double-Blind Placebo-Controlled Trial.
topicPolypodium Leucotomos Skin Photoprotection Randomized Trial
claimBackground/Objectives : Oral photoprotection is gaining attention as a complementary approach to conventional sun protection.
evidence level2
citationKeršmanc P (2025)
sourceEffects of Eight-Week Supplementation Containing Red Orange and <i>Polypodium leucotomos</i> Extracts on UVB-Induced Skin Responses: A Randomized Double-Blind Placebo-Controlled Trial.
topicPolypodium Leucotomos Skin Photoprotection Randomized Trial
claimThis randomized double-blind placebo-controlled study evaluated the effects of an 8-week dietary intervention with a syrup supplement containing Polypodium leucotomos extract (PLE), Red Orange Extract (ROE), and vitamins A, C, D, and E on minimal erythema dose (MED), UVB-induced erythema (Δ a* ), and pigmentation changes (ΔMI).
evidence level2
citationKeršmanc P (2025)
sourceEffects of Eight-Week Supplementation Containing Red Orange and <i>Polypodium leucotomos</i> Extracts on UVB-Induced Skin Responses: A Randomized Double-Blind Placebo-Controlled Trial.