topicMelatonin Sleep Jet Lag Meta-Analysis
claimAlthough empirical studies show variable effects on competition outcomes, likely due to individual and situational differences, the consensus is that significant travel without proper adjustment is a risk factor for performance decrement [].
evidence level3
citationHatamiya Nicolas (2026)
sourceOptimizing Athlete Travel for Performance: A Scientific Blueprint for Athletes, Coaches, and Sports Medicine Staff
topicMelatonin Sleep Jet Lag Meta-Analysis
claimIn addition to timezone shifts, the general fatigue of long-haul travel may itself hinder recovery by disturbing sleep patterns even without circadian misalignment, though direct evidence for this independent effect remains limited.
evidence level3
citationHatamiya Nicolas (2026)
sourceOptimizing Athlete Travel for Performance: A Scientific Blueprint for Athletes, Coaches, and Sports Medicine Staff
topicMelatonin Sleep Jet Lag Meta-Analysis
claimIndeed, a landmark study of elite athletes found that traveling to international destinations with > 5 h time differences was associated with a two- to threefold higher risk of illness, such as upper respiratory infections, in the week following travel [].
evidence level3
citationHatamiya Nicolas (2026)
sourceOptimizing Athlete Travel for Performance: A Scientific Blueprint for Athletes, Coaches, and Sports Medicine Staff
topicMelatonin Sleep Jet Lag Meta-Analysis
claimAs athlete travel becomes more prevalent, particularly long-haul travel crossing multiple timezones, the impacts of travel on athlete performance should be considered as they pertain to jet lag, travel-related fatigue, fueling, gastrointestinal disturbances, environmental conditions, illness, and soft-tissue injury.
evidence level3
citationHatamiya Nicolas (2026)
sourceOptimizing Athlete Travel for Performance: A Scientific Blueprint for Athletes, Coaches, and Sports Medicine Staff
topicMelatonin Sleep Jet Lag Meta-Analysis
claimThis includes the activation of adenylate cyclase, increased cAMP levels, and subsequent activation of protein kinase A (PKA).
evidence level3
citationWani Pinaki D. (2026)
sourceMelatonin and sleep: Exploring its role in regulating the circadian rhythm and sleep-wake cycle
topicMelatonin Sleep Jet Lag Meta-Analysis
claimChronic or inappropriate light exposure, such as during night shifts or jet lag, can disrupt this regulation, leading to altered melatonin rhythms and associated sleep disturbances.[] 14 The role of light in regulating melatonin has clinical implications, as appropriately timed light exposure or avoidance can help manage circadian rhythm disorders.
evidence level3
citationWani Pinaki D. (2026)
sourceMelatonin and sleep: Exploring its role in regulating the circadian rhythm and sleep-wake cycle
topicMelatonin Sleep Jet Lag Meta-Analysis
claimElevated nocturnal melatonin levels reduce core body temperature, a physiological change associated with sleep initiation.
evidence level3
citationWani Pinaki D. (2026)
sourceMelatonin and sleep: Exploring its role in regulating the circadian rhythm and sleep-wake cycle
topicMelatonin Sleep Jet Lag Meta-Analysis
claim1 Sleep is a fundamental physiological process essential for maintaining overall health and well-being.
evidence level3
citationWani Pinaki D. (2026)
sourceMelatonin and sleep: Exploring its role in regulating the circadian rhythm and sleep-wake cycle