topicL-Theanine Sleep Latency Randomized Trial
claimResults : The mean THI score decreased from 40.8 at baseline to 30.9 at the end of the study ( p = 0.012), and the percentage of patients with THI grade 1 (no handicap) increased from 3.3% to 20%.
evidence level3
citationCepeda Uceta M (2026)
sourceBenefits of a Natural Dietary Supplement for Tinnitus: An Observational Prospective Exploratory Study.
topicL-Theanine Sleep Latency Randomized Trial
claimA decrease in the mean frequency of tinnitus from 2417.4 Hz to 1603.3 Hz ( p = 0.519) was found.
evidence level3
citationCepeda Uceta M (2026)
sourceBenefits of a Natural Dietary Supplement for Tinnitus: An Observational Prospective Exploratory Study.
topicL-Theanine Sleep Latency Randomized Trial
claimConclusions : The administration of a natural-based dietary supplement composed of L-theanine, Ginkgo biloba , melatonin, GABA, zinc, selenium, and group B vitamins during 90 days in patients with tinnitus was associated with a significant increase in QoL by reducing tinnitus-associated handicap and anxiety.
evidence level3
citationCepeda Uceta M (2026)
sourceBenefits of a Natural Dietary Supplement for Tinnitus: An Observational Prospective Exploratory Study.
topicL-Theanine Sleep Latency Randomized Trial
claimBackground/Objectives : The objective of the study was to assess the benefits on quality of life (QoL) of a natural-based dietary supplement in patients with tinnitus.
evidence level3
citationCepeda Uceta M (2026)
sourceBenefits of a Natural Dietary Supplement for Tinnitus: An Observational Prospective Exploratory Study.
topicL-Theanine Sleep Latency Randomized Trial
claimSleep is a complex biological process whose evolutionary purpose has remained equivocal for quite some time.More recently, however, compelling evidence has emerged, leading to recognition of the numerous metabolic and physiological functions sleep contributes to and actively supports.
evidence level4
citationConti Federica (2026)
sourceDietary Protocols to Promote and Improve Restful Sleep: A Narrative Review
topicL-Theanine Sleep Latency Randomized Trial
claimEpidemiological studies have revealed that sleep deprivation is associated with an increased risk of all-cause mortality,alongside numerous chronic conditions imposing a heavy burden on our healthcare and socioeconomic systems alike,including cardiovascular disease, stroke, obesity, type 2 diabetes, and various types of cancer and neurological disorders.
evidence level4
citationConti Federica (2026)
sourceDietary Protocols to Promote and Improve Restful Sleep: A Narrative Review
topicL-Theanine Sleep Latency Randomized Trial
claimThe scope of this narrative review is to summarize the available evidence on the mechanisms of action and potential benefits of the above-listed nutrients in the context of acute or chronic sleep disturbances.
evidence level4
citationConti Federica (2026)
sourceDietary Protocols to Promote and Improve Restful Sleep: A Narrative Review
topicL-Theanine Sleep Latency Randomized Trial
claim, , Over the past few decades, there has been an increasing appreciation of the negative impact of sleep disturbances and circadian misalignments on all aspects of human health and performance, ranging from objective alertness, learning, memory, and cognition to emotional regulation, social wellbeing and, most remarkably, physical health.
evidence level4
citationConti Federica (2026)
sourceDietary Protocols to Promote and Improve Restful Sleep: A Narrative Review