Structured evidence table for Iron Sleep Quality Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Iron Sleep Quality Meta-Analysis | However, the evidence base for TCM pharmacologic interventions in hemodialysis-related RLS remains unclear. | 1 | Zhang J (2026) | Efficacy and safety of pharmacological treatments for restless legs syndrome in hemodialysis patients: a systematic review and meta-analysis. |
| Iron Sleep Quality Meta-Analysis | Pharmacologic therapy significantly improved IRLS scores (MD -7.84), sleep quality (SMD -0.82), and quality of life (SMD 0.48). | 1 | Zhang J (2026) | Efficacy and safety of pharmacological treatments for restless legs syndrome in hemodialysis patients: a systematic review and meta-analysis. |
| Iron Sleep Quality Meta-Analysis | A heatmap further revealed that dopaminergic agents were associated with the highest frequency of adverse events, particularly nausea, hypotension, and augmentation. | 1 | Zhang J (2026) | Efficacy and safety of pharmacological treatments for restless legs syndrome in hemodialysis patients: a systematic review and meta-analysis. |
| Iron Sleep Quality Meta-Analysis | Background Restless Legs Syndrome (RLS) is highly prevalent among adults receiving maintenance hemodialysis and significantly impairs sleep, psychological well-being, and quality of life. | 1 | Zhang J (2026) | Efficacy and safety of pharmacological treatments for restless legs syndrome in hemodialysis patients: a systematic review and meta-analysis. |
| Iron Sleep Quality Meta-Analysis | This review synthesizes evidence on the prevalence, outcomes, and pathophysiology of RLS in various neurological disorders, including Parkinson's disease, multiple sclerosis, migraine, dementia, stroke, epilepsy, and peripheral neuropathy. | 4 | Ghattas K (2026) | Restless Legs Syndrome and Neurological Comorbidities: A Narrative Review. |
| Iron Sleep Quality Meta-Analysis | In stroke and multiple sclerosis, RLS is associated with structural lesions at specific locations, such as the pons or spinal cord. | 4 | Ghattas K (2026) | Restless Legs Syndrome and Neurological Comorbidities: A Narrative Review. |
| Iron Sleep Quality Meta-Analysis | RLS in neurological conditions often worsens sleep quality, mood, and fatigue, and contributes to reduced quality of life and worse outcomes. | 4 | Ghattas K (2026) | Restless Legs Syndrome and Neurological Comorbidities: A Narrative Review. |
| Iron Sleep Quality Meta-Analysis | Restless legs syndrome (RLS) is a common yet underrecognized neurological disorder characterized by uncomfortable sensations and an irresistible urge to move he legs, typically following a circadian pattern. | 4 | Ghattas K (2026) | Restless Legs Syndrome and Neurological Comorbidities: A Narrative Review. |
Source documents