topicHyaluronic Acid Skin Hydration Meta-Analysis
claimAs for clinical studies, the intervention increased skin hydration (MD = 2.12, 95% CI [1.02; 3.21]) while decreased TEWL (MD = -0.68, 95% CI [-1.21; -0.16]).
evidence level1
citationLiang Y (2026)
sourceImpact of Antioxidant-Rich Whole Foods or Supplements on Skin Health: A Systematic Review and Meta-Analysis of Preclinical and Clinical Studies.
topicHyaluronic Acid Skin Hydration Meta-Analysis
claimConclusions Antioxidant-rich whole foods or supplements intake improved overall skin health and skin disorder conditions.
evidence level1
citationLiang Y (2026)
sourceImpact of Antioxidant-Rich Whole Foods or Supplements on Skin Health: A Systematic Review and Meta-Analysis of Preclinical and Clinical Studies.
topicHyaluronic Acid Skin Hydration Meta-Analysis
claimBackground Antioxidant supplements have been reported to confer benefits for skin health; however, these effects remain inconclusive and lack systematic evaluation.
evidence level1
citationLiang Y (2026)
sourceImpact of Antioxidant-Rich Whole Foods or Supplements on Skin Health: A Systematic Review and Meta-Analysis of Preclinical and Clinical Studies.
topicHyaluronic Acid Skin Hydration Meta-Analysis
claimMethods This systematic review and meta-analysis assessed the impact of antioxidant-rich whole foods or supplements on various skin health outcomes by compiling data from five databases, including 94 eligible preclinical and clinical studies.
evidence level1
citationLiang Y (2026)
sourceImpact of Antioxidant-Rich Whole Foods or Supplements on Skin Health: A Systematic Review and Meta-Analysis of Preclinical and Clinical Studies.
topicHyaluronic Acid Skin Hydration Meta-Analysis
claimAQP Inhibition ofChannels and Associated Stress Response T11014 8 9 10 11 NHEKs were pretreated with DFP00173 50–100 μM (DFP, TargetMol, TGM‐, United States), a known AQP3 inhibitor [], or Phloretin 250 μM (Sigma, P7912, Germany), a general AQP inhibitor [,,] for 1 h.
evidence level4
citationMarquardt Kay (2026)
sourceReviving the Skin From Within: Mechanistic Insights Into a Well‐Tolerated Dermal Filler— CPM ‐ HA20G
topicHyaluronic Acid Skin Hydration Meta-Analysis
claimSamples were then lysed in NP40 lysis buffer and analyzed by western blotting for associated stress responses via pP38/tP38.
evidence level4
citationMarquardt Kay (2026)
sourceReviving the Skin From Within: Mechanistic Insights Into a Well‐Tolerated Dermal Filler— CPM ‐ HA20G
topicHyaluronic Acid Skin Hydration Meta-Analysis
claimCorneometer hydration analysis showed that both glycerol and CPM‐HA20G significantly increased hydration compared to the average control by an average of 31% ± 11% ( < 0.001) and 10% ± 11% ( < 0.05), respectively (Figure ).
evidence level4
citationMarquardt Kay (2026)
sourceReviving the Skin From Within: Mechanistic Insights Into a Well‐Tolerated Dermal Filler— CPM ‐ HA20G
topicHyaluronic Acid Skin Hydration Meta-Analysis
claimAQP CPM HA HU IHC NHEKs NMF ROS SC SHE TEWL μCT 1 1 Skin quality is a foundational element of facial attractiveness and a primary motivator for seeking aesthetic treatments.
evidence level4
citationMarquardt Kay (2026)
sourceReviving the Skin From Within: Mechanistic Insights Into a Well‐Tolerated Dermal Filler— CPM ‐ HA20G