Hyaluronic Acid Joint Stiffness Randomized Trial Evidence Table

Structured evidence table for Hyaluronic Acid Joint Stiffness Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Hyaluronic Acid Joint Stiffness Randomized TrialConclusion Ultrasound-guided hyaluronic acid injection and supervised rehabilitation produced comparable and clinically meaningful improvements in pain, function, and shoulder mobility in frozen-phase adhesive capsulitis.2Chang CY (2026)Efficacy of ultrasound-guided intra-articular hyaluronic acid injection in the management of adhesive capsulitis: a randomized controlled trial.
Hyaluronic Acid Joint Stiffness Randomized TrialObjective To compare the efficacy and safety of ultrasound-guided intra-articular hyaluronic acid injection versus supervised rehabilitation in patients with frozen-phase adhesive capsulitis.2Chang CY (2026)Efficacy of ultrasound-guided intra-articular hyaluronic acid injection in the management of adhesive capsulitis: a randomized controlled trial.
Hyaluronic Acid Joint Stiffness Randomized TrialDesign Single-center, parallel-group, randomized controlled trial with 26-week follow-up.2Chang CY (2026)Efficacy of ultrasound-guided intra-articular hyaluronic acid injection in the management of adhesive capsulitis: a randomized controlled trial.
Hyaluronic Acid Joint Stiffness Randomized TrialThese findings provided high-level evidence challenging the clinical benefit of cross-linked HAs.2Kanitnate S (2026)Efficacy of Ultra-high and High Molecular Weight Cross-Linked Hyaluronic Acids Compared with Saline in Knee Osteoarthritis: A Randomized Controlled Trial.
Hyaluronic Acid Joint Stiffness Randomized TrialIntroduction Intra-articular hyaluronic acid (HA) injections are widely used for knee osteoarthritis (OA) to reduce pain and improve function.2Kanitnate S (2026)Efficacy of Ultra-high and High Molecular Weight Cross-Linked Hyaluronic Acids Compared with Saline in Knee Osteoarthritis: A Randomized Controlled Trial.
Hyaluronic Acid Joint Stiffness Randomized TrialThis study aimed to compare the efficacy of 2 single-injection, ultra-high, and high molecular weight (HMW) cross-linked HAs against a saline placebo for symptomatic knee OA.2Kanitnate S (2026)Efficacy of Ultra-high and High Molecular Weight Cross-Linked Hyaluronic Acids Compared with Saline in Knee Osteoarthritis: A Randomized Controlled Trial.
topicHyaluronic Acid Joint Stiffness Randomized Trial
claimConclusion Ultrasound-guided hyaluronic acid injection and supervised rehabilitation produced comparable and clinically meaningful improvements in pain, function, and shoulder mobility in frozen-phase adhesive capsulitis.
evidence level2
citationChang CY (2026)
sourceEfficacy of ultrasound-guided intra-articular hyaluronic acid injection in the management of adhesive capsulitis: a randomized controlled trial.
topicHyaluronic Acid Joint Stiffness Randomized Trial
claimObjective To compare the efficacy and safety of ultrasound-guided intra-articular hyaluronic acid injection versus supervised rehabilitation in patients with frozen-phase adhesive capsulitis.
evidence level2
citationChang CY (2026)
sourceEfficacy of ultrasound-guided intra-articular hyaluronic acid injection in the management of adhesive capsulitis: a randomized controlled trial.
topicHyaluronic Acid Joint Stiffness Randomized Trial
claimDesign Single-center, parallel-group, randomized controlled trial with 26-week follow-up.
evidence level2
citationChang CY (2026)
sourceEfficacy of ultrasound-guided intra-articular hyaluronic acid injection in the management of adhesive capsulitis: a randomized controlled trial.
topicHyaluronic Acid Joint Stiffness Randomized Trial
claimThese findings provided high-level evidence challenging the clinical benefit of cross-linked HAs.
evidence level2
citationKanitnate S (2026)
sourceEfficacy of Ultra-high and High Molecular Weight Cross-Linked Hyaluronic Acids Compared with Saline in Knee Osteoarthritis: A Randomized Controlled Trial.
topicHyaluronic Acid Joint Stiffness Randomized Trial
claimIntroduction Intra-articular hyaluronic acid (HA) injections are widely used for knee osteoarthritis (OA) to reduce pain and improve function.
evidence level2
citationKanitnate S (2026)
sourceEfficacy of Ultra-high and High Molecular Weight Cross-Linked Hyaluronic Acids Compared with Saline in Knee Osteoarthritis: A Randomized Controlled Trial.
topicHyaluronic Acid Joint Stiffness Randomized Trial
claimThis study aimed to compare the efficacy of 2 single-injection, ultra-high, and high molecular weight (HMW) cross-linked HAs against a saline placebo for symptomatic knee OA.
evidence level2
citationKanitnate S (2026)
sourceEfficacy of Ultra-high and High Molecular Weight Cross-Linked Hyaluronic Acids Compared with Saline in Knee Osteoarthritis: A Randomized Controlled Trial.

Source documents

  1. Efficacy of ultrasound-guided intra-articular hyaluronic acid injection in the management of adhesive capsulitis: a randomized controlled trial.
  2. Efficacy of Ultra-high and High Molecular Weight Cross-Linked Hyaluronic Acids Compared with Saline in Knee Osteoarthritis: A Randomized Controlled Trial.