evidence table
Hyaluronic Acid Joint Pain Randomized Trial Evidence Table
Structured evidence table for Hyaluronic Acid Joint Pain Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Hyaluronic Acid Joint Pain Randomized Trial | Conclusion Ultrasound-guided hyaluronic acid injection and supervised rehabilitation produced comparable and clinically meaningful improvements in pain, function, and shoulder mobility in frozen-phase adhesive capsulitis. | 2 | Chang CY (2026) | Efficacy of ultrasound-guided intra-articular hyaluronic acid injection in the management of adhesive capsulitis: a randomized controlled trial. |
| Hyaluronic Acid Joint Pain Randomized Trial | Objective To compare the efficacy and safety of ultrasound-guided intra-articular hyaluronic acid injection versus supervised rehabilitation in patients with frozen-phase adhesive capsulitis. | 2 | Chang CY (2026) | Efficacy of ultrasound-guided intra-articular hyaluronic acid injection in the management of adhesive capsulitis: a randomized controlled trial. |
| Hyaluronic Acid Joint Pain Randomized Trial | Design Single-center, parallel-group, randomized controlled trial with 26-week follow-up. | 2 | Chang CY (2026) | Efficacy of ultrasound-guided intra-articular hyaluronic acid injection in the management of adhesive capsulitis: a randomized controlled trial. |
| Hyaluronic Acid Joint Pain Randomized Trial | 1 2 3 4 5 Osteoarthritis (OA) is a degenerative disease characterized by the progressive degeneration of articular cartilage, the development of osteophytes, alterations in subchondral bone and synovial hyperplasia, clinically responsible for increasing disability and reduced quality of life []. | 2 | Riglet Louis (2026) | Efficacy and safety of a combination of platelet-rich plasma with non-crosslinked hyaluronic acid versus a crosslinked hyaluronic acid, in single-injection for knee osteoarthritis. Randomized, controlled, multicenter, non-inferiority trial |
| Hyaluronic Acid Joint Pain Randomized Trial | In vitro studies also suggest improved stimulation of chondrogenesis, and a reduction in both inflammation and chondrocyte catabolism [,]. | 2 | Riglet Louis (2026) | Efficacy and safety of a combination of platelet-rich plasma with non-crosslinked hyaluronic acid versus a crosslinked hyaluronic acid, in single-injection for knee osteoarthritis. Randomized, controlled, multicenter, non-inferiority trial |
| Hyaluronic Acid Joint Pain Randomized Trial | [] have shown that the release of growth factors is increased in vitro on the fifth day following the addition of HA, which remains to be confirmed clinically. | 2 | Riglet Louis (2026) | Efficacy and safety of a combination of platelet-rich plasma with non-crosslinked hyaluronic acid versus a crosslinked hyaluronic acid, in single-injection for knee osteoarthritis. Randomized, controlled, multicenter, non-inferiority trial |
| Hyaluronic Acid Joint Pain Randomized Trial | Knee OA is characterized by multiple symptoms such as mechanical pain, stiffness and disabling inflammatory flare-ups that can reduce locomotor autonomy and promote falls [,]. | 2 | Riglet Louis (2026) | Efficacy and safety of a combination of platelet-rich plasma with non-crosslinked hyaluronic acid versus a crosslinked hyaluronic acid, in single-injection for knee osteoarthritis. Randomized, controlled, multicenter, non-inferiority trial |
Source documents
- Efficacy of ultrasound-guided intra-articular hyaluronic acid injection in the management of adhesive capsulitis: a randomized controlled trial.
- Efficacy and safety of a combination of platelet-rich plasma with non-crosslinked hyaluronic acid versus a crosslinked hyaluronic acid, in single-injection for knee osteoarthritis. Randomized, controlled, multicenter, non-inferiority trial