topicCurcumin Mood Meta-Analysis
claimDiscussion Overall, Zingiberaceae-derived interventions may improve memory-related outcomes, but the evidence is very uncertain due to substantial heterogeneity, the small number of studies, risk of bias in some trials, and variability in populations, formulations, and outcome measures.
evidence level1
citationVictoria-Montesinos D (2026)
sourceEffects of Zingiberaceae-derived interventions on memory-related and other cognitive outcomes in adults: a systematic review and meta-analysis.
topicCurcumin Mood Meta-Analysis
claimIntroduction Cognitive impairment and age-related cognitive decline are major public health concerns, and nutraceutical strategies targeting modifiable biological pathways have attracted growing interest.
evidence level1
citationVictoria-Montesinos D (2026)
sourceEffects of Zingiberaceae-derived interventions on memory-related and other cognitive outcomes in adults: a systematic review and meta-analysis.
topicCurcumin Mood Meta-Analysis
claimCompounds derived from the Zingiberaceae family, including curcumin, turmeric, ginger, and related preparations, have been investigated for their potential neuroprotective effects, but their clinical impact on specific cognitive domains remains unclear.
evidence level1
citationVictoria-Montesinos D (2026)
sourceEffects of Zingiberaceae-derived interventions on memory-related and other cognitive outcomes in adults: a systematic review and meta-analysis.
topicCurcumin Mood Meta-Analysis
claim1 2 Depression is a leading cause of disability worldwide and is characterised by sustained low mood, anhedonia, anergia, and a range of associated cognitive and somatic symptoms [].
evidence level4
citationMuacevic Alexander (2026)
sourceThe Role of Saffron in the Treatment of Depression: A Literature Review
topicCurcumin Mood Meta-Analysis
claimThis literature review summarises key randomised controlled trials (RCTs), meta-analyses, safety data, dosing patterns, and guideline positioning for saffron in depressive disorders, with emphasis on adult major depressive disorder (MDD) and related depressive symptomatology.
evidence level4
citationMuacevic Alexander (2026)
sourceThe Role of Saffron in the Treatment of Depression: A Literature Review
topicCurcumin Mood Meta-Analysis
claimMethods Crocus sativus' Databases and search strategy: A targeted search was undertaken in PubMed (primary database), with supplementary searching via Google Scholar and reference-list screening of key trials and evidence syntheses included in the bibliography.
evidence level4
citationMuacevic Alexander (2026)
sourceThe Role of Saffron in the Treatment of Depression: A Literature Review
topicCurcumin Mood Meta-Analysis
claimAlthough standard first-line approaches, such as lifestyle interventions, psychotherapy, and antidepressant medication, are effective for many patients, a meaningful minority experience partial response, intolerable adverse effects, or poor adherence [].
evidence level4
citationMuacevic Alexander (2026)
sourceThe Role of Saffron in the Treatment of Depression: A Literature Review