Structured evidence table for Cocoa Sleep Quality Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Cocoa Sleep Quality Meta-Analysis | Polyphenols strengthen the intestinal barrier and reduce endotoxemia; cocoa bean shell extracts protected against oxysterol‐induced intestinal damage and improved gut microbiota composition in preclinical models (Alia et al. ). | 3 | Akif Adnan (2026) | Dietary Polyphenols in Non‐Communicable Chronic Diseases: Neuro–Enteric Mechanisms, Multi‐Omics Biomarkers and Translational Opportunities |
| Cocoa Sleep Quality Meta-Analysis | While many epidemiological studies correlate polyphenol‐rich diets (e.g., Mediterranean diet) with reduced NCCD risk, causality is uncertain due to confounding and measurement error. | 3 | Akif Adnan (2026) | Dietary Polyphenols in Non‐Communicable Chronic Diseases: Neuro–Enteric Mechanisms, Multi‐Omics Biomarkers and Translational Opportunities |
| Cocoa Sleep Quality Meta-Analysis | Controlled trials provide more robust evidence but vary widely in doses, formulations, populations and endpoints. | 3 | Akif Adnan (2026) | Dietary Polyphenols in Non‐Communicable Chronic Diseases: Neuro–Enteric Mechanisms, Multi‐Omics Biomarkers and Translational Opportunities |
| Cocoa Sleep Quality Meta-Analysis | AMP BBB CNS COMT COSMOS CRP (hs‐CRP) CSF EGCG ENB‐2 (ENB) ENS EVOO FMD GAD‐7 (GAD) GM‐CSF (GM) HDL HOMA‐IR (HOMA) IBS IL IR LDL LPS MCI MMSE NADPH NCCD (NCCDs) PHGG PHQ‐9 (PHQ) PSQI PWV RBANS RCT SCFA SD TNF (TNF‐α) 2024 Non‐communicable chronic diseases account for the majority of morbidity and mortality worldwide. | 3 | Akif Adnan (2026) | Dietary Polyphenols in Non‐Communicable Chronic Diseases: Neuro–Enteric Mechanisms, Multi‐Omics Biomarkers and Translational Opportunities |
| Cocoa Sleep Quality Meta-Analysis | 1 2 3 5 6 7 8 9 More than two billion people are at risk of micronutrient deficiencies, which often involve multiple, rather than single, nutrients [,]. | 4 | Muacevic Alexander (2026) | A to Z of Health: An Evidence-Based Narrative Review of Multivitamin-Multimineral and Nutraceutical Supplementation |
| Cocoa Sleep Quality Meta-Analysis | They are widely used to help individuals meet their daily nutrient requirements, support overall health, and address increased nutritional needs associated with pregnancy, aging, and illness. | 4 | Muacevic Alexander (2026) | A to Z of Health: An Evidence-Based Narrative Review of Multivitamin-Multimineral and Nutraceutical Supplementation |
| Cocoa Sleep Quality Meta-Analysis | According to the National Health and Nutrition Examination Survey, MVM use in the USA increased from 35% in 1999-2000 [] to 49-52% between 2011 and 2014, with higher usage among women than men [-]. | 4 | Muacevic Alexander (2026) | A to Z of Health: An Evidence-Based Narrative Review of Multivitamin-Multimineral and Nutraceutical Supplementation |
| Cocoa Sleep Quality Meta-Analysis | The most common deficiencies include vitamin A, folic acid, vitamin D, iron, iodine, and zinc, especially among children and women in low- and middle-income countries [-]. | 4 | Muacevic Alexander (2026) | A to Z of Health: An Evidence-Based Narrative Review of Multivitamin-Multimineral and Nutraceutical Supplementation |
Source documents