Quick Answer
Soy Isoflavones Skin Health Meta-Analysis has evidence relevant to safety, limits, and clinician-discussion contexts, but conclusions should stay close to the cited sources. One representative finding is: The aim of this study is to expand upon existing evidence of the benefits of soy isoflavones in postmenopausal women with Fitzpatrick skin types I–IV, by examining the effects of a 12-week supplementation period on parameters of skin health and determining whether these effects are S-equol dependent.
Key Takeaways
- 01The aim of this study is to expand upon existing evidence of the benefits of soy isoflavones in postmenopausal women with Fitzpatrick skin types I–IV, by examining the effects of a 12-week supplementation period on parameters of skin health and determining whether these effects are S-equol dependent. [Vijayakumar Vineetha (2025)]
- 02These analyses were performed in R v4.3.3, using thefunction for backward stepwise variable selection to remove unnecessary predictors, using AIC criteria ().-values of the linear regressions were corrected following Benjamini-Hochberg procedure to reduce the risk of type I errors. [Vijayakumar Vineetha (2025)]
- 03p < – p < p < p < n = p = Figures 4B E Figure 4B Supplementary Table 2 Figures 4C D Supplementary Table 2 Figure 4E Supplementary Table 2 In addition, supplementation with Novasoy®400 significantly increased the concentration of all four metabolites from D0 to D84, as determined by the Wilcoxon test ( 0.05) (). [Vijayakumar Vineetha (2025)]
- 041 2 3 4 Menopause triggers a decline in oestrogen levels, causing various physiological alterations, including accelerated skin aging (). [Vijayakumar Vineetha (2025)]
The current Migaku evidence database contains 2 reusable source documents for Soy Isoflavones Skin Health Meta-Analysis. This answer focuses on safety, limits, and clinician-discussion contexts.
- The aim of this study is to expand upon existing evidence of the benefits of soy isoflavones in postmenopausal women with Fitzpatrick skin types I–IV, by examining the effects of a 12-week supplementation period on parameters of skin health and determining whether these effects are S-equol dependent. [Vijayakumar Vineetha (2025); evidence level 2]
- These analyses were performed in R v4.3.3, using thefunction for backward stepwise variable selection to remove unnecessary predictors, using AIC criteria ().-values of the linear regressions were corrected following Benjamini-Hochberg procedure to reduce the risk of type I errors. [Vijayakumar Vineetha (2025); evidence level 2]
- p < – p < p < p < n = p = Figures 4B E Figure 4B Supplementary Table 2 Figures 4C D Supplementary Table 2 Figure 4E Supplementary Table 2 In addition, supplementation with Novasoy®400 significantly increased the concentration of all four metabolites from D0 to D84, as determined by the Wilcoxon test ( 0.05) (). [Vijayakumar Vineetha (2025); evidence level 2]
- 1 2 3 4 Menopause triggers a decline in oestrogen levels, causing various physiological alterations, including accelerated skin aging (). [Vijayakumar Vineetha (2025); evidence level 2]
- They have been found in numerous plant species belonging to the Leguminosae family, including soy (), kudzu (), and red clover (). [Wójciak Magdalena (2024); evidence level 4]
Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording.
This page is educational. People with medical conditions, pregnancy, medication use, or unusual symptoms should ask a qualified clinician before changing supplements, medication, or treatment routines.
Sources