skin aging

Soy Isoflavones Skin Hydration Randomized Trial Evidence Table

Structured evidence table for Soy Isoflavones Skin Hydration Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Soy Isoflavones Skin Hydration Randomized TrialThe aim of this study is to expand upon existing evidence of the benefits of soy isoflavones in postmenopausal women with Fitzpatrick skin types I–IV, by examining the effects of a 12-week supplementation period on parameters of skin health and determining whether these effects are S-equol dependent.2Vijayakumar Vineetha (2025)S-equol status modulates skin response to soy isoflavones in postmenopausal women: results from a randomized placebo-controlled pilot trial
Soy Isoflavones Skin Hydration Randomized TrialThese analyses were performed in R v4.3.3, using thefunction for backward stepwise variable selection to remove unnecessary predictors, using AIC criteria ().-values of the linear regressions were corrected following Benjamini-Hochberg procedure to reduce the risk of type I errors.2Vijayakumar Vineetha (2025)S-equol status modulates skin response to soy isoflavones in postmenopausal women: results from a randomized placebo-controlled pilot trial
Soy Isoflavones Skin Hydration Randomized Trialp&#8239;< &#8211; p&#8239;< p&#8239;< p&#8239;< n&#8239;= p&#8239;= Figures 4B E Figure 4B Supplementary Table 2 Figures 4C D Supplementary Table 2 Figure 4E Supplementary Table 2 In addition, supplementation with Novasoy&#174;400 significantly increased the concentration of all four metabolites from D0 to D84, as determined by the Wilcoxon test (&#8239;0.05) ().2Vijayakumar Vineetha (2025)S-equol status modulates skin response to soy isoflavones in postmenopausal women: results from a randomized placebo-controlled pilot trial
Soy Isoflavones Skin Hydration Randomized Trial1 2 3 4 Menopause triggers a decline in oestrogen levels, causing various physiological alterations, including accelerated skin aging ().2Vijayakumar Vineetha (2025)S-equol status modulates skin response to soy isoflavones in postmenopausal women: results from a randomized placebo-controlled pilot trial
Soy Isoflavones Skin Hydration Randomized TrialPreliminary findings from multiple studies indicate that dietary intake of soy-derived isoflavones exert beneficial effects on the skin including defense against oxidant damage, stimulation of collagen synthesis, and increased hydration.2Rizzo J (2023)Soy Protein Containing Isoflavones Improves Facial Signs of Photoaging and Skin Hydration in Postmenopausal Women: Results of a Prospective Randomized Double-Blind Controlled Trial.
Soy Isoflavones Skin Hydration Randomized TrialThis study aims to investigate how oral supplementation of a soy protein isolate with added isoflavones (SPII) affects components of photoaging such as facial wrinkles and dyspigmentation, and skin biophysical measures such as skin hydration and sebum excretion in postmenopausal women.2Rizzo J (2023)Soy Protein Containing Isoflavones Improves Facial Signs of Photoaging and Skin Hydration in Postmenopausal Women: Results of a Prospective Randomized Double-Blind Controlled Trial.
topicSoy Isoflavones Skin Hydration Randomized Trial
claimThe aim of this study is to expand upon existing evidence of the benefits of soy isoflavones in postmenopausal women with Fitzpatrick skin types I&#8211;IV, by examining the effects of a 12-week supplementation period on parameters of skin health and determining whether these effects are S-equol dependent.
evidence level2
citationVijayakumar Vineetha (2025)
sourceS-equol status modulates skin response to soy isoflavones in postmenopausal women: results from a randomized placebo-controlled pilot trial
topicSoy Isoflavones Skin Hydration Randomized Trial
claimThese analyses were performed in R v4.3.3, using thefunction for backward stepwise variable selection to remove unnecessary predictors, using AIC criteria ().-values of the linear regressions were corrected following Benjamini-Hochberg procedure to reduce the risk of type I errors.
evidence level2
citationVijayakumar Vineetha (2025)
sourceS-equol status modulates skin response to soy isoflavones in postmenopausal women: results from a randomized placebo-controlled pilot trial
topicSoy Isoflavones Skin Hydration Randomized Trial
claimp&#8239;< &#8211; p&#8239;< p&#8239;< p&#8239;< n&#8239;= p&#8239;= Figures 4B E Figure 4B Supplementary Table 2 Figures 4C D Supplementary Table 2 Figure 4E Supplementary Table 2 In addition, supplementation with Novasoy&#174;400 significantly increased the concentration of all four metabolites from D0 to D84, as determined by the Wilcoxon test (&#8239;0.05) ().
evidence level2
citationVijayakumar Vineetha (2025)
sourceS-equol status modulates skin response to soy isoflavones in postmenopausal women: results from a randomized placebo-controlled pilot trial
topicSoy Isoflavones Skin Hydration Randomized Trial
claim1 2 3 4 Menopause triggers a decline in oestrogen levels, causing various physiological alterations, including accelerated skin aging ().
evidence level2
citationVijayakumar Vineetha (2025)
sourceS-equol status modulates skin response to soy isoflavones in postmenopausal women: results from a randomized placebo-controlled pilot trial
topicSoy Isoflavones Skin Hydration Randomized Trial
claimPreliminary findings from multiple studies indicate that dietary intake of soy-derived isoflavones exert beneficial effects on the skin including defense against oxidant damage, stimulation of collagen synthesis, and increased hydration.
evidence level2
citationRizzo J (2023)
sourceSoy Protein Containing Isoflavones Improves Facial Signs of Photoaging and Skin Hydration in Postmenopausal Women: Results of a Prospective Randomized Double-Blind Controlled Trial.
topicSoy Isoflavones Skin Hydration Randomized Trial
claimThis study aims to investigate how oral supplementation of a soy protein isolate with added isoflavones (SPII) affects components of photoaging such as facial wrinkles and dyspigmentation, and skin biophysical measures such as skin hydration and sebum excretion in postmenopausal women.
evidence level2
citationRizzo J (2023)
sourceSoy Protein Containing Isoflavones Improves Facial Signs of Photoaging and Skin Hydration in Postmenopausal Women: Results of a Prospective Randomized Double-Blind Controlled Trial.

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Source documents

  1. S-equol status modulates skin response to soy isoflavones in postmenopausal women: results from a randomized placebo-controlled pilot trial
  2. Soy Protein Containing Isoflavones Improves Facial Signs of Photoaging and Skin Hydration in Postmenopausal Women: Results of a Prospective Randomized Double-Blind Controlled Trial.