Does Lemon Verbena Sleep Quality Randomized Trial work?

Updated October 2026

Quick Answer

Lemon Verbena Sleep Quality Randomized Trial has evidence relevant to strength of evidence and what the studies can or cannot prove, but conclusions should stay close to the cited sources. One representative finding is: Plasma nocturnal melatonin levels also increased significantly in the experimental group (199.7 ± 135.3 vs.

Key Takeaways

  • 01Plasma nocturnal melatonin levels also increased significantly in the experimental group (199.7 ± 135.3 vs. [Pérez-Piñero S (2024)]
  • 02Changes in anthropometric parameters and physical activity levels were not found. [Pérez-Piñero S (2024)]
  • 03In summary, a dietary supplement of lemon verbena administered for 3 months was associated with a significant improvement in sleep quality as compared with placebo in a population of healthy subjects with sleep problems. [Pérez-Piñero S (2024)]
  • 04Seventy-one healthy subjects with sleep disturbances participated in a randomized, double-blind controlled trial in which dietary supplementation with an extract of Aloysia citrodora (lemon verbena) ( n = 33) or placebo ( n = 38) was administered for 90 days. [Pérez-Piñero S (2024)]
The current Migaku evidence database contains 2 reusable source documents for Lemon Verbena Sleep Quality Randomized Trial. This answer focuses on strength of evidence and what the studies can or cannot prove. - Plasma nocturnal melatonin levels also increased significantly in the experimental group (199.7 ± 135.3 vs. [Pérez-Piñero S (2024); evidence level 2] - Changes in anthropometric parameters and physical activity levels were not found. [Pérez-Piñero S (2024); evidence level 2] - In summary, a dietary supplement of lemon verbena administered for 3 months was associated with a significant improvement in sleep quality as compared with placebo in a population of healthy subjects with sleep problems. [Pérez-Piñero S (2024); evidence level 2] - Seventy-one healthy subjects with sleep disturbances participated in a randomized, double-blind controlled trial in which dietary supplementation with an extract of Aloysia citrodora (lemon verbena) ( n = 33) or placebo ( n = 38) was administered for 90 days. [Pérez-Piñero S (2024); evidence level 2] - Quantitative EEG analysis revealed that LVE treatment reduced wakefulness while significantly enhancing REM and NREM sleep's duration, indicating its potential sleep-promoting effects. [Choi M (2025); evidence level 4] Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording. This page is educational. People with medical conditions, pregnancy, medication use, or unusual symptoms should ask a qualified clinician before changing supplements, medication, or treatment routines.

Sources

  1. Dietary Supplementation with an Extract of <i>Aloysia citrodora</i> (Lemon verbena) Improves Sleep Quality in Healthy Subjects: A Randomized Double-Blind Controlled Study.
  2. Lemon Verbena Extract Enhances Sleep Quality and Duration via Modulation of Adenosine A1 and GABA&lt;sub&gt;A&lt;/sub&gt; Receptors in Pentobarbital-Induced and Polysomnography-Based Sleep Models.