topicLemon Verbena Sleep Quality Randomized Trial
claimPlasma nocturnal melatonin levels also increased significantly in the experimental group (199.7 ± 135.3 vs.
evidence level2
citationPérez-Piñero S (2024)
sourceDietary Supplementation with an Extract of <i>Aloysia citrodora</i> (Lemon verbena) Improves Sleep Quality in Healthy Subjects: A Randomized Double-Blind Controlled Study.
topicLemon Verbena Sleep Quality Randomized Trial
claimChanges in anthropometric parameters and physical activity levels were not found.
evidence level2
citationPérez-Piñero S (2024)
sourceDietary Supplementation with an Extract of <i>Aloysia citrodora</i> (Lemon verbena) Improves Sleep Quality in Healthy Subjects: A Randomized Double-Blind Controlled Study.
topicLemon Verbena Sleep Quality Randomized Trial
claimIn summary, a dietary supplement of lemon verbena administered for 3 months was associated with a significant improvement in sleep quality as compared with placebo in a population of healthy subjects with sleep problems.
evidence level2
citationPérez-Piñero S (2024)
sourceDietary Supplementation with an Extract of <i>Aloysia citrodora</i> (Lemon verbena) Improves Sleep Quality in Healthy Subjects: A Randomized Double-Blind Controlled Study.
topicLemon Verbena Sleep Quality Randomized Trial
claimSeventy-one healthy subjects with sleep disturbances participated in a randomized, double-blind controlled trial in which dietary supplementation with an extract of Aloysia citrodora (lemon verbena) ( n = 33) or placebo ( n = 38) was administered for 90 days.
evidence level2
citationPérez-Piñero S (2024)
sourceDietary Supplementation with an Extract of <i>Aloysia citrodora</i> (Lemon verbena) Improves Sleep Quality in Healthy Subjects: A Randomized Double-Blind Controlled Study.
topicLemon Verbena Sleep Quality Randomized Trial
claimQuantitative EEG analysis revealed that LVE treatment reduced wakefulness while significantly enhancing REM and NREM sleep's duration, indicating its potential sleep-promoting effects.
evidence level4
citationChoi M (2025)
sourceLemon Verbena Extract Enhances Sleep Quality and Duration via Modulation of Adenosine A1 and GABA<sub>A</sub> Receptors in Pentobarbital-Induced and Polysomnography-Based Sleep Models.
topicLemon Verbena Sleep Quality Randomized Trial
claimThis study investigated the effects of lemon verbena extract (LVE) on sleep regulation using both a pentobarbital-induced sleep model and an EEG-based sleep assessment model in mice.
evidence level4
citationChoi M (2025)
sourceLemon Verbena Extract Enhances Sleep Quality and Duration via Modulation of Adenosine A1 and GABA<sub>A</sub> Receptors in Pentobarbital-Induced and Polysomnography-Based Sleep Models.
topicLemon Verbena Sleep Quality Randomized Trial
claimTo elucidate its potential mechanisms, mice were randomly assigned to five groups: control, positive control (diazepam, 2 mg/kg b.w.), and three LVE-treated groups receiving 40, 80, or 160 mg/kg b.w.
evidence level4
citationChoi M (2025)
sourceLemon Verbena Extract Enhances Sleep Quality and Duration via Modulation of Adenosine A1 and GABA<sub>A</sub> Receptors in Pentobarbital-Induced and Polysomnography-Based Sleep Models.