Is Lemon Verbena Sleep Quality Randomized Trial safe?

Updated October 2026

Quick Answer

Lemon Verbena Sleep Quality Randomized Trial has evidence relevant to safety, limits, and clinician-discussion contexts, but conclusions should stay close to the cited sources. One representative finding is: Plasma nocturnal melatonin levels also increased significantly in the experimental group (199.7 ± 135.3 vs.

Key Takeaways

  • 01Plasma nocturnal melatonin levels also increased significantly in the experimental group (199.7 ± 135.3 vs. [Pérez-Piñero S (2024)]
  • 02Changes in anthropometric parameters and physical activity levels were not found. [Pérez-Piñero S (2024)]
  • 03In summary, a dietary supplement of lemon verbena administered for 3 months was associated with a significant improvement in sleep quality as compared with placebo in a population of healthy subjects with sleep problems. [Pérez-Piñero S (2024)]
  • 04Seventy-one healthy subjects with sleep disturbances participated in a randomized, double-blind controlled trial in which dietary supplementation with an extract of Aloysia citrodora (lemon verbena) ( n = 33) or placebo ( n = 38) was administered for 90 days. [Pérez-Piñero S (2024)]
The current Migaku evidence database contains 2 reusable source documents for Lemon Verbena Sleep Quality Randomized Trial. This answer focuses on safety, limits, and clinician-discussion contexts. - Plasma nocturnal melatonin levels also increased significantly in the experimental group (199.7 ± 135.3 vs. [Pérez-Piñero S (2024); evidence level 2] - Changes in anthropometric parameters and physical activity levels were not found. [Pérez-Piñero S (2024); evidence level 2] - In summary, a dietary supplement of lemon verbena administered for 3 months was associated with a significant improvement in sleep quality as compared with placebo in a population of healthy subjects with sleep problems. [Pérez-Piñero S (2024); evidence level 2] - Seventy-one healthy subjects with sleep disturbances participated in a randomized, double-blind controlled trial in which dietary supplementation with an extract of Aloysia citrodora (lemon verbena) ( n = 33) or placebo ( n = 38) was administered for 90 days. [Pérez-Piñero S (2024); evidence level 2] - Quantitative EEG analysis revealed that LVE treatment reduced wakefulness while significantly enhancing REM and NREM sleep's duration, indicating its potential sleep-promoting effects. [Choi M (2025); evidence level 4] Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording. This page is educational. People with medical conditions, pregnancy, medication use, or unusual symptoms should ask a qualified clinician before changing supplements, medication, or treatment routines.

Sources

  1. Dietary Supplementation with an Extract of <i>Aloysia citrodora</i> (Lemon verbena) Improves Sleep Quality in Healthy Subjects: A Randomized Double-Blind Controlled Study.
  2. Lemon Verbena Extract Enhances Sleep Quality and Duration via Modulation of Adenosine A1 and GABA&lt;sub&gt;A&lt;/sub&gt; Receptors in Pentobarbital-Induced and Polysomnography-Based Sleep Models.